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An Extended Duration of the Pre-Operative Hospitalization is Associated with an Increased Risk of Healthcare-Associated Infections after Cardiac Surgery
by
Koller, Lorenz
, Laufer, Günther
, Kazem, Niema
, Fleck, Tatjana
, Distelmaier, Klaus
, Schnaubelt, Sebastian
, Pilz, Arnold
, Steinlechner, Barbara
, Andreas, Martin
, Goliasch, Georg
, Toma, Aurel
, Sulzgruber, Patrick
, Niessner, Alexander
, Winter, Max-Paul
, Hengstenberg, Christian
in
692/308/174
/ 692/700/478/174
/ Antibiotics
/ Cardiac Surgical Procedures - adverse effects
/ Cross Infection - diagnosis
/ Cross Infection - epidemiology
/ Cross Infection - etiology
/ Female
/ Health risks
/ Heart
/ Heart surgery
/ Hospital Mortality
/ Hospitalization
/ Hospitals
/ Humanities and Social Sciences
/ Humans
/ Incidence
/ Length of Stay
/ Male
/ multidisciplinary
/ Nosocomial infections
/ Observational studies
/ Odds Ratio
/ Patients
/ Postoperative Complications
/ Preoperative Period
/ Regression analysis
/ Science
/ Science (multidisciplinary)
/ Surgical outcomes
2020
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An Extended Duration of the Pre-Operative Hospitalization is Associated with an Increased Risk of Healthcare-Associated Infections after Cardiac Surgery
by
Koller, Lorenz
, Laufer, Günther
, Kazem, Niema
, Fleck, Tatjana
, Distelmaier, Klaus
, Schnaubelt, Sebastian
, Pilz, Arnold
, Steinlechner, Barbara
, Andreas, Martin
, Goliasch, Georg
, Toma, Aurel
, Sulzgruber, Patrick
, Niessner, Alexander
, Winter, Max-Paul
, Hengstenberg, Christian
in
692/308/174
/ 692/700/478/174
/ Antibiotics
/ Cardiac Surgical Procedures - adverse effects
/ Cross Infection - diagnosis
/ Cross Infection - epidemiology
/ Cross Infection - etiology
/ Female
/ Health risks
/ Heart
/ Heart surgery
/ Hospital Mortality
/ Hospitalization
/ Hospitals
/ Humanities and Social Sciences
/ Humans
/ Incidence
/ Length of Stay
/ Male
/ multidisciplinary
/ Nosocomial infections
/ Observational studies
/ Odds Ratio
/ Patients
/ Postoperative Complications
/ Preoperative Period
/ Regression analysis
/ Science
/ Science (multidisciplinary)
/ Surgical outcomes
2020
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An Extended Duration of the Pre-Operative Hospitalization is Associated with an Increased Risk of Healthcare-Associated Infections after Cardiac Surgery
by
Koller, Lorenz
, Laufer, Günther
, Kazem, Niema
, Fleck, Tatjana
, Distelmaier, Klaus
, Schnaubelt, Sebastian
, Pilz, Arnold
, Steinlechner, Barbara
, Andreas, Martin
, Goliasch, Georg
, Toma, Aurel
, Sulzgruber, Patrick
, Niessner, Alexander
, Winter, Max-Paul
, Hengstenberg, Christian
in
692/308/174
/ 692/700/478/174
/ Antibiotics
/ Cardiac Surgical Procedures - adverse effects
/ Cross Infection - diagnosis
/ Cross Infection - epidemiology
/ Cross Infection - etiology
/ Female
/ Health risks
/ Heart
/ Heart surgery
/ Hospital Mortality
/ Hospitalization
/ Hospitals
/ Humanities and Social Sciences
/ Humans
/ Incidence
/ Length of Stay
/ Male
/ multidisciplinary
/ Nosocomial infections
/ Observational studies
/ Odds Ratio
/ Patients
/ Postoperative Complications
/ Preoperative Period
/ Regression analysis
/ Science
/ Science (multidisciplinary)
/ Surgical outcomes
2020
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An Extended Duration of the Pre-Operative Hospitalization is Associated with an Increased Risk of Healthcare-Associated Infections after Cardiac Surgery
Journal Article
An Extended Duration of the Pre-Operative Hospitalization is Associated with an Increased Risk of Healthcare-Associated Infections after Cardiac Surgery
2020
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Overview
Nosocomial infections are a common complication in clinical practice with major impact on surgical success and patient outcome. The probability of nosocomial infections is rapidly increasing during hospitalization. Therefore, we investigated the impact of a prolonged pre-operative hospital stay on the development of post-operative infection. Within this prospective observational study, 200 patients scheduled for elective cardiac surgery were enrolled. Patients were followed during hospital admission and screened for the development of nosocomial infection. Logistic regression analysis was used to assess the impact of a prolonged pre-operative hospital stay on the development of infection. A total of 195 patients were suitable for the final analysis. We found a strong and direct association of the duration of pre-operative hospital stay and the number of patients developing infection (+23.5%; p = 0.006). Additionally, the length of patients’ pre-operative hospital stay was independently associated with the development of post-operative nosocomial infection, with an adjusted OR per day of 1.38 (95%CI: 1.02–1.86; p = 0.036). A prolonged pre-operative hospital stay was significantly associated with the development of nosocomial infection after cardiac surgery. Those findings need to be considered in future clinical patient management in order to prevent unnecessary antibiotic use and potential harm to patients.
Publisher
Nature Publishing Group UK,Nature Publishing Group
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