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Opsoclonus-myoclonus syndrome, a post-infectious neurologic complication of COVID-19: case series and review of literature
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Opsoclonus-myoclonus syndrome, a post-infectious neurologic complication of COVID-19: case series and review of literature
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Opsoclonus-myoclonus syndrome, a post-infectious neurologic complication of COVID-19: case series and review of literature
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Journal Article
Opsoclonus-myoclonus syndrome, a post-infectious neurologic complication of COVID-19: case series and review of literature
2021
Overview
Opsoclonus-myoclonus-ataxia syndrome is a heterogeneous constellation of symptoms ranging from full combination of these three neurological findings to varying degrees of isolated individual sign. Since the emergence of coronavirus disease 2019 (COVID-19), neurological symptoms, syndromes, and complications associated with this multi-organ viral infection have been reported and the various aspects of neurological involvement are increasingly uncovered. As a neuro-inflammatory disorder, one would expect to observe opsoclonus-myoclonus syndrome after a prevalent viral infection in a pandemic scale, as it has been the case for many other neuro-inflammatory syndromes. We report seven cases of opsoclonus-myoclonus syndrome presumably parainfectious in nature and discuss their phenomenology, their possible pathophysiological relationship to COVID-19, and diagnostic and treatment strategy in each case. Finally, we review the relevant data in the literature regarding the opsoclonus-myoclonus syndrome and possible similar cases associated with COVID-19 and its diagnostic importance for clinicians in various fields of medicine encountering COVID-19 patients and its complications.
Publisher
Springer International Publishing
Subject
/ Anticonvulsants - therapeutic use
/ Azithromycin - therapeutic use
/ Biomedical and Life Sciences
/ Clonazepam - therapeutic use
/ COVID-19 - diagnostic imaging
/ Dyspnea - diagnostic imaging
/ Female
/ Humans
/ Hydroxychloroquine - therapeutic use
/ Levetiracetam - therapeutic use
/ Male
/ Myalgia - diagnostic imaging
/ Opsoclonus-Myoclonus Syndrome - diagnostic imaging
/ Opsoclonus-Myoclonus Syndrome - drug therapy
/ Opsoclonus-Myoclonus Syndrome - etiology
/ Opsoclonus-Myoclonus Syndrome - physiopathology
/ Oseltamivir - therapeutic use
/ Review
/ Valproic Acid - therapeutic use
/ Virology
