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Encephalocele following a periconceptional exposure to efavirenz: a case report
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Encephalocele following a periconceptional exposure to efavirenz: a case report
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Journal Article
Encephalocele following a periconceptional exposure to efavirenz: a case report
2013
Overview
The use of Efaverinz in reproductive age women needs caution as its use in the first trimster of pregnancy is reportedly associated with an increased risk of neural tube defect (NTD) in the newborn. This concern is based on evidence from animal studies and two human case reports. We report here yet another case of encephalocele born from a mother who was taking efaverenze during conception and the first 8 weeks of gestation, the critical time in the pathogenesis of NTDs.
Publisher
Nature Publishing Group US,Nature Publishing Group
Subject
/ Adult
/ Age
/ Benzoxazines - adverse effects
/ Encephalocele - chemically induced
/ Female
/ Fetuses
/ HIV
/ HIV Infections - drug therapy
/ Human immunodeficiency virus
/ Humans
/ Medicine
/ perinatal-neonatal-case-presentation
/ Pregnancy Complications, Infectious - drug therapy
/ Reverse Transcriptase Inhibitors - adverse effects
/ Toxicity
/ Women
