Asset Details
Do you wish to reserve the book?
Single pyruvate intake induces blood alkalization and modification of resting metabolism in humans
Hey, we have placed the reservation for you!
By the way, why not check out events that you can attend while you pick your title.
Oops! Something went wrong.
Looks like we were not able to place the reservation. Kindly try again later.
Are you sure you want to remove the book from the shelf?
Single pyruvate intake induces blood alkalization and modification of resting metabolism in humans
Do you wish to request the book?
Single pyruvate intake induces blood alkalization and modification of resting metabolism in humans
Please be aware that the book you have requested cannot be checked out. If you would like to checkout this book, you can reserve another copy
We have requested the book for you!
Your request is successful and it will be processed during the Library working hours. Please check the status of your request in My Requests.
Oops! Something went wrong.
Looks like we were not able to place your request. Kindly try again later.
Journal Article
Single pyruvate intake induces blood alkalization and modification of resting metabolism in humans
2015
Overview
Three separate studies were performed with the aim to 1) determine the effect of a single sodium pyruvate intake on the blood acid-base status in males and females; 2) compare the effect of sodium and calcium pyruvate salts and establish their role in the lipolysis rate; and 3) quantify the effect of single pyruvate intake on the resting energy metabolism.
In all, 48 individuals completed three separate studies. In all the studies, participants consumed a single dose of pyruvate 0.1 g/kg 60 min before commencing the measurements. The whole blood pH, bicarbonate concentration, base excess or plasma glycerol, free fatty acids, glucose concentrations, or resting energy expenditure and calculated respiratory exchange ratio were determined. The analysis of variance for repeated measurements was performed to examine the interaction between treatment and time.
The single dose of sodium pyruvate induced blood alkalization, which was more marked in the male than in the female participants. Following the ingestion of sodium or calcium pyruvate, the blood acid-base parameters were higher than in the placebo trial. Furthermore, 3-h postingestion glycerol was lower in both pyruvate trials than in placebo. Resting energy expenditure did not differ between the trials; however, carbohydrate oxidation was increased after sodium pyruvate ingestion.
Pyruvate intake induced mild alkalization in a sex-dependent fashion. Moreover, it accelerated carbohydrate metabolism and delayed the rate of glycerol appearance in the blood, but had no effect on the resting energy expenditure. Furthermore, sodium salt seems to have had a greater effect on the blood buffering level than calcium salt.
•Pyruvate intake induced mild alkalization in a sex-dependent fashion.•Sodium salt has a greater effect on the blood acid-base parameters than calcium salt.•Pyruvate consumption delayed the rate of glycerol appearance in the blood.•Pyruvate ingestion increased respiratory exchange ratio.
Publisher
Elsevier Inc,Elsevier Limited
Subject
Acid-Base Equilibrium - drug effects
/ Adult
/ Age
/ Basal Metabolism - drug effects
/ Blood
/ blood pH
/ Body fat
/ Calcium
/ Carbohydrate Metabolism - drug effects
/ Fatty Acids, Nonesterified - blood
/ Female
/ females
/ Football
/ Gastroenterology and Hepatology
/ glucose
/ Glycerol
/ Humans
/ Male
/ males
/ placebos
/ Plasma
/ Rodents
/ Sodium
/ Studies
