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Migraine Treatment: Current Acute Medications and Their Potential Mechanisms of Action
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Migraine Treatment: Current Acute Medications and Their Potential Mechanisms of Action
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Journal Article
Migraine Treatment: Current Acute Medications and Their Potential Mechanisms of Action
2018
Overview
Migraine is a common and disabling primary headache disorder with a significant socioeconomic burden. The management of migraine is multifaceted and is generally dichotomized into acute and preventive strategies, with several treatment modalities. The aims of acute pharmacological treatment are to rapidly restore function with minimal recurrence, with the avoidance of side effects. The choice of pharmacological treatment is individualized, and is based on the consideration of the characteristics of the migraine attack, the patient's concomitant medical problems, and treatment preferences. Notwithstanding, a good understanding of the pharmacodynamic and pharmacokinetic properties of the various drug options is essential to guide therapy. The current approach and concepts relevant to the acute pharmacological treatment of migraine will be explored in this review.
Publisher
Elsevier Inc,Springer International Publishing,Springer Nature B.V
Subject
Acetaminophen - therapeutic use
/ Analgesics, Opioid - therapeutic use
/ Animals
/ Anti-Inflammatory Agents, Non-Steroidal - therapeutic use
/ Biomedical and Life Sciences
/ Dopamine Antagonists - therapeutic use
/ Ergot Alkaloids - therapeutic use
/ Headache
/ Humans
/ Migraine
/ Migraine Disorders - drug therapy
/ Migraine Disorders - physiopathology
/ Review
