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Lecanemab in Early Alzheimer’s Disease
by
Aisen, Paul
, Froelich, Lutz
, Watson, David
, Li, David
, Kramer, Lynn D.
, Gee, Michelle
, Sabbagh, Marwan
, Dhadda, Shobha
, Swanson, Chad J.
, Bateman, Randall J.
, van Dyck, Christopher H.
, Reyderman, Larisa
, Chen, Christopher
, Iwatsubo, Takeshi
, Vellas, Bruno
, Cohen, Sharon
, Kanekiyo, Michio
, Katayama, Sadao
, Irizarry, Michael
in
Activities of Daily Living
/ Aging
/ Alzheimer Disease
/ Alzheimer Disease - diagnostic imaging
/ Alzheimer Disease - drug therapy
/ Alzheimer's disease
/ Amyloid beta-Peptides - cerebrospinal fluid
/ Antibodies, Monoclonal, Humanized - adverse effects
/ Antibodies, Monoclonal, Humanized - pharmacology
/ Antibodies, Monoclonal, Humanized - therapeutic use
/ Biomarkers
/ Body weight
/ Cerebrospinal fluid
/ Clinical trials
/ Cognition - drug effects
/ Cognitive ability
/ Coronaviruses
/ COVID-19
/ Dementia
/ Dementia disorders
/ Double-Blind Method
/ Drug dosages
/ Edema
/ FDA approval
/ Geriatrics
/ Humans
/ Immunoglobulin G
/ Intravenous administration
/ Life Sciences
/ Magnetic resonance imaging
/ Memory
/ Mild cognitive impairment
/ Monoclonal antibodies
/ Neurodegenerative diseases
/ Neuroimaging
/ Neurology
/ Neurosurgery
/ Nootropic Agents - adverse effects
/ Nootropic Agents - pharmacology
/ Nootropic Agents - therapeutic use
/ Placebos
/ Positron emission tomography
/ Psychiatry
/ Psychiatry General
/ Technical communication
2023
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Lecanemab in Early Alzheimer’s Disease
by
Aisen, Paul
, Froelich, Lutz
, Watson, David
, Li, David
, Kramer, Lynn D.
, Gee, Michelle
, Sabbagh, Marwan
, Dhadda, Shobha
, Swanson, Chad J.
, Bateman, Randall J.
, van Dyck, Christopher H.
, Reyderman, Larisa
, Chen, Christopher
, Iwatsubo, Takeshi
, Vellas, Bruno
, Cohen, Sharon
, Kanekiyo, Michio
, Katayama, Sadao
, Irizarry, Michael
in
Activities of Daily Living
/ Aging
/ Alzheimer Disease
/ Alzheimer Disease - diagnostic imaging
/ Alzheimer Disease - drug therapy
/ Alzheimer's disease
/ Amyloid beta-Peptides - cerebrospinal fluid
/ Antibodies, Monoclonal, Humanized - adverse effects
/ Antibodies, Monoclonal, Humanized - pharmacology
/ Antibodies, Monoclonal, Humanized - therapeutic use
/ Biomarkers
/ Body weight
/ Cerebrospinal fluid
/ Clinical trials
/ Cognition - drug effects
/ Cognitive ability
/ Coronaviruses
/ COVID-19
/ Dementia
/ Dementia disorders
/ Double-Blind Method
/ Drug dosages
/ Edema
/ FDA approval
/ Geriatrics
/ Humans
/ Immunoglobulin G
/ Intravenous administration
/ Life Sciences
/ Magnetic resonance imaging
/ Memory
/ Mild cognitive impairment
/ Monoclonal antibodies
/ Neurodegenerative diseases
/ Neuroimaging
/ Neurology
/ Neurosurgery
/ Nootropic Agents - adverse effects
/ Nootropic Agents - pharmacology
/ Nootropic Agents - therapeutic use
/ Placebos
/ Positron emission tomography
/ Psychiatry
/ Psychiatry General
/ Technical communication
2023
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Lecanemab in Early Alzheimer’s Disease
by
Aisen, Paul
, Froelich, Lutz
, Watson, David
, Li, David
, Kramer, Lynn D.
, Gee, Michelle
, Sabbagh, Marwan
, Dhadda, Shobha
, Swanson, Chad J.
, Bateman, Randall J.
, van Dyck, Christopher H.
, Reyderman, Larisa
, Chen, Christopher
, Iwatsubo, Takeshi
, Vellas, Bruno
, Cohen, Sharon
, Kanekiyo, Michio
, Katayama, Sadao
, Irizarry, Michael
in
Activities of Daily Living
/ Aging
/ Alzheimer Disease
/ Alzheimer Disease - diagnostic imaging
/ Alzheimer Disease - drug therapy
/ Alzheimer's disease
/ Amyloid beta-Peptides - cerebrospinal fluid
/ Antibodies, Monoclonal, Humanized - adverse effects
/ Antibodies, Monoclonal, Humanized - pharmacology
/ Antibodies, Monoclonal, Humanized - therapeutic use
/ Biomarkers
/ Body weight
/ Cerebrospinal fluid
/ Clinical trials
/ Cognition - drug effects
/ Cognitive ability
/ Coronaviruses
/ COVID-19
/ Dementia
/ Dementia disorders
/ Double-Blind Method
/ Drug dosages
/ Edema
/ FDA approval
/ Geriatrics
/ Humans
/ Immunoglobulin G
/ Intravenous administration
/ Life Sciences
/ Magnetic resonance imaging
/ Memory
/ Mild cognitive impairment
/ Monoclonal antibodies
/ Neurodegenerative diseases
/ Neuroimaging
/ Neurology
/ Neurosurgery
/ Nootropic Agents - adverse effects
/ Nootropic Agents - pharmacology
/ Nootropic Agents - therapeutic use
/ Placebos
/ Positron emission tomography
/ Psychiatry
/ Psychiatry General
/ Technical communication
2023
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Journal Article
Lecanemab in Early Alzheimer’s Disease
2023
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Overview
In a phase 3 trial, participants with early Alzheimer’s disease who received the monoclonal antibody lecanemab had less decline on measures of cognition and function at 18 months than those who received placebo.
Publisher
Massachusetts Medical Society
Subject
/ Aging
/ Alzheimer Disease - diagnostic imaging
/ Alzheimer Disease - drug therapy
/ Amyloid beta-Peptides - cerebrospinal fluid
/ Antibodies, Monoclonal, Humanized - adverse effects
/ Antibodies, Monoclonal, Humanized - pharmacology
/ Antibodies, Monoclonal, Humanized - therapeutic use
/ COVID-19
/ Dementia
/ Edema
/ Humans
/ Memory
/ Nootropic Agents - adverse effects
/ Nootropic Agents - pharmacology
/ Nootropic Agents - therapeutic use
/ Placebos
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