Asset Details
Do you wish to reserve the book?
Improvement in strategies for the non-invasive prenatal diagnosis of Huntington disease
Hey, we have placed the reservation for you!
By the way, why not check out events that you can attend while you pick your title.
Oops! Something went wrong.
Looks like we were not able to place the reservation. Kindly try again later.
Are you sure you want to remove the book from the shelf?
Improvement in strategies for the non-invasive prenatal diagnosis of Huntington disease
Do you wish to request the book?
Improvement in strategies for the non-invasive prenatal diagnosis of Huntington disease
Please be aware that the book you have requested cannot be checked out. If you would like to checkout this book, you can reserve another copy
We have requested the book for you!
Your request is successful and it will be processed during the Library working hours. Please check the status of your request in My Requests.
Oops! Something went wrong.
Looks like we were not able to place your request. Kindly try again later.
Journal Article
Improvement in strategies for the non-invasive prenatal diagnosis of Huntington disease
2008
Overview
Purpose
We focused on the improvements of prenatal diagnosis by the analysis of DNA from maternal plasma, using Huntington disease as a model of disease.
Methods
We studied plasma from a pregnancy at risk of having a fetus affected with Huntington disease by the use of two direct analysis of the mutation and polymorphic STRs.
Results
Direct methods were not informative. Analysis with STRs revealed the presence of the allele that does not co-segregate with the disease, thus the fetus was healthy.
Conclusions
This strategy is very useful to face complex cases when the direct study is not informative not only for Huntington disease but also for many other disorders.
Publisher
Springer US,Springer Nature B.V
Subject
/ Female
/ Fetuses
/ Genetics
/ Humans
/ Huntington Disease - diagnosis
/ Huntington Disease - genetics
/ Male
/ Medicine
/ Mutation
/ Plasma
