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A Comparison of Rate Control and Rhythm Control in Patients with Recurrent Persistent Atrial Fibrillation
by
Darmanata, Julius I
, Bosker, Hans A
, Said, Salah A
, Tijssen, Jan G.P
, Timmermans, Alphons J.M
, Kingma, J. Herre
, Kamp, Otto
, Crijns, Harry J.G.M
, Van Gelder, Isabelle C
, Hagens, Vincent E
, Kingma, Tsjerk
in
Adrenergic beta-Antagonists - therapeutic use
/ Aged
/ Anti-Arrhythmia Agents - therapeutic use
/ Anticoagulants - therapeutic use
/ Atrial Fibrillation - complications
/ Atrial Fibrillation - mortality
/ Atrial Fibrillation - therapy
/ Biological and medical sciences
/ Calcium Channel Blockers - therapeutic use
/ Cardiac arrhythmia
/ Cardiac dysrhythmias
/ Cardiology. Vascular system
/ Combined Modality Therapy
/ Comparative analysis
/ Disease-Free Survival
/ Drug therapy
/ Electric Countershock
/ Female
/ Heart
/ Heart Rate
/ Humans
/ Hypertension - complications
/ Male
/ Medical procedures
/ Medical sciences
/ Recurrence
/ Sex Factors
2002
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A Comparison of Rate Control and Rhythm Control in Patients with Recurrent Persistent Atrial Fibrillation
by
Darmanata, Julius I
, Bosker, Hans A
, Said, Salah A
, Tijssen, Jan G.P
, Timmermans, Alphons J.M
, Kingma, J. Herre
, Kamp, Otto
, Crijns, Harry J.G.M
, Van Gelder, Isabelle C
, Hagens, Vincent E
, Kingma, Tsjerk
in
Adrenergic beta-Antagonists - therapeutic use
/ Aged
/ Anti-Arrhythmia Agents - therapeutic use
/ Anticoagulants - therapeutic use
/ Atrial Fibrillation - complications
/ Atrial Fibrillation - mortality
/ Atrial Fibrillation - therapy
/ Biological and medical sciences
/ Calcium Channel Blockers - therapeutic use
/ Cardiac arrhythmia
/ Cardiac dysrhythmias
/ Cardiology. Vascular system
/ Combined Modality Therapy
/ Comparative analysis
/ Disease-Free Survival
/ Drug therapy
/ Electric Countershock
/ Female
/ Heart
/ Heart Rate
/ Humans
/ Hypertension - complications
/ Male
/ Medical procedures
/ Medical sciences
/ Recurrence
/ Sex Factors
2002
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A Comparison of Rate Control and Rhythm Control in Patients with Recurrent Persistent Atrial Fibrillation
by
Darmanata, Julius I
, Bosker, Hans A
, Said, Salah A
, Tijssen, Jan G.P
, Timmermans, Alphons J.M
, Kingma, J. Herre
, Kamp, Otto
, Crijns, Harry J.G.M
, Van Gelder, Isabelle C
, Hagens, Vincent E
, Kingma, Tsjerk
in
Adrenergic beta-Antagonists - therapeutic use
/ Aged
/ Anti-Arrhythmia Agents - therapeutic use
/ Anticoagulants - therapeutic use
/ Atrial Fibrillation - complications
/ Atrial Fibrillation - mortality
/ Atrial Fibrillation - therapy
/ Biological and medical sciences
/ Calcium Channel Blockers - therapeutic use
/ Cardiac arrhythmia
/ Cardiac dysrhythmias
/ Cardiology. Vascular system
/ Combined Modality Therapy
/ Comparative analysis
/ Disease-Free Survival
/ Drug therapy
/ Electric Countershock
/ Female
/ Heart
/ Heart Rate
/ Humans
/ Hypertension - complications
/ Male
/ Medical procedures
/ Medical sciences
/ Recurrence
/ Sex Factors
2002
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A Comparison of Rate Control and Rhythm Control in Patients with Recurrent Persistent Atrial Fibrillation
Journal Article
A Comparison of Rate Control and Rhythm Control in Patients with Recurrent Persistent Atrial Fibrillation
2002
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Overview
This study is the European counterpart of the North American study of atrial fibrillation reported in this issue of the
Journal
. Although the European study was smaller, the findings in the two studies were quite similar. Rate control was not inferior to rhythm control and should be regarded as appropriate for the management of persistent atrial fibrillation.
Atrial fibrillation is not a benign condition.
1
,
2
For many clinicians, maintenance of sinus rhythm is the main therapeutic goal. In patients with persistent atrial fibrillation, repeated electrical cardioversion and prophylactic antiarrhythmic drugs are used to maintain sinus rhythm.
3
However, frequent recurrences of atrial fibrillation and adverse effects of drugs decrease the potential benefits of electrical cardioversion.
4
–
6
Also, the beneficial effects of rhythm control may be nullified by life-threatening cardiovascular events. Such events may be related not to the rhythm but, rather, to underlying cardiovascular abnormalities.
4
Since the rhythm is not the main determinant of the prognosis, it is . . .
Publisher
Massachusetts Medical Society
Subject
Adrenergic beta-Antagonists - therapeutic use
/ Aged
/ Anti-Arrhythmia Agents - therapeutic use
/ Anticoagulants - therapeutic use
/ Atrial Fibrillation - complications
/ Atrial Fibrillation - mortality
/ Atrial Fibrillation - therapy
/ Biological and medical sciences
/ Calcium Channel Blockers - therapeutic use
/ Female
/ Heart
/ Humans
/ Hypertension - complications
/ Male
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