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SARS-CoV-2 T Cell Responses Elicited by COVID-19 Vaccines or Infection Are Expected to Remain Robust against Omicron
by
Ahmed, Syed Faraz
, Quadeer, Ahmed Abdul
, McKay, Matthew R.
in
Antibodies
/ Communication
/ Coronaviruses
/ COVID-19
/ COVID-19 - immunology
/ COVID-19 - virology
/ COVID-19 infection
/ COVID-19 vaccines
/ COVID-19 Vaccines - immunology
/ Disease transmission
/ Epitopes
/ Epitopes, T-Lymphocyte - genetics
/ Epitopes, T-Lymphocyte - immunology
/ Humans
/ Infections
/ Lymphocytes
/ Lymphocytes T
/ Medical research
/ Mutation
/ mutations
/ Omicron
/ Peptides
/ Proteins
/ SARS-CoV-2
/ SARS-CoV-2 - genetics
/ SARS-CoV-2 - immunology
/ Severe acute respiratory syndrome coronavirus 2
/ Spike Glycoprotein, Coronavirus - genetics
/ Spike Glycoprotein, Coronavirus - immunology
/ Spike protein
/ T cell epitopes
/ T-lymphocytes
/ T-Lymphocytes - immunology
/ Vaccines
/ variants
/ Viral infections
/ Viral Proteins - metabolism
2022
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SARS-CoV-2 T Cell Responses Elicited by COVID-19 Vaccines or Infection Are Expected to Remain Robust against Omicron
by
Ahmed, Syed Faraz
, Quadeer, Ahmed Abdul
, McKay, Matthew R.
in
Antibodies
/ Communication
/ Coronaviruses
/ COVID-19
/ COVID-19 - immunology
/ COVID-19 - virology
/ COVID-19 infection
/ COVID-19 vaccines
/ COVID-19 Vaccines - immunology
/ Disease transmission
/ Epitopes
/ Epitopes, T-Lymphocyte - genetics
/ Epitopes, T-Lymphocyte - immunology
/ Humans
/ Infections
/ Lymphocytes
/ Lymphocytes T
/ Medical research
/ Mutation
/ mutations
/ Omicron
/ Peptides
/ Proteins
/ SARS-CoV-2
/ SARS-CoV-2 - genetics
/ SARS-CoV-2 - immunology
/ Severe acute respiratory syndrome coronavirus 2
/ Spike Glycoprotein, Coronavirus - genetics
/ Spike Glycoprotein, Coronavirus - immunology
/ Spike protein
/ T cell epitopes
/ T-lymphocytes
/ T-Lymphocytes - immunology
/ Vaccines
/ variants
/ Viral infections
/ Viral Proteins - metabolism
2022
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SARS-CoV-2 T Cell Responses Elicited by COVID-19 Vaccines or Infection Are Expected to Remain Robust against Omicron
by
Ahmed, Syed Faraz
, Quadeer, Ahmed Abdul
, McKay, Matthew R.
in
Antibodies
/ Communication
/ Coronaviruses
/ COVID-19
/ COVID-19 - immunology
/ COVID-19 - virology
/ COVID-19 infection
/ COVID-19 vaccines
/ COVID-19 Vaccines - immunology
/ Disease transmission
/ Epitopes
/ Epitopes, T-Lymphocyte - genetics
/ Epitopes, T-Lymphocyte - immunology
/ Humans
/ Infections
/ Lymphocytes
/ Lymphocytes T
/ Medical research
/ Mutation
/ mutations
/ Omicron
/ Peptides
/ Proteins
/ SARS-CoV-2
/ SARS-CoV-2 - genetics
/ SARS-CoV-2 - immunology
/ Severe acute respiratory syndrome coronavirus 2
/ Spike Glycoprotein, Coronavirus - genetics
/ Spike Glycoprotein, Coronavirus - immunology
/ Spike protein
/ T cell epitopes
/ T-lymphocytes
/ T-Lymphocytes - immunology
/ Vaccines
/ variants
/ Viral infections
/ Viral Proteins - metabolism
2022
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SARS-CoV-2 T Cell Responses Elicited by COVID-19 Vaccines or Infection Are Expected to Remain Robust against Omicron
Journal Article
SARS-CoV-2 T Cell Responses Elicited by COVID-19 Vaccines or Infection Are Expected to Remain Robust against Omicron
2022
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Overview
Omicron, the most recent SARS-CoV-2 variant of concern (VOC), harbours multiple mutations in the spike protein that were not observed in previous VOCs. Initial studies suggest Omicron to substantially reduce the neutralizing capability of antibodies induced from vaccines and previous infection. However, its effect on T cell responses remains to be determined. Here, we assess the effect of Omicron mutations on known T cell epitopes and report data suggesting T cell responses to remain broadly robust against this new variant.
Publisher
MDPI AG,MDPI
Subject
/ COVID-19
/ COVID-19 Vaccines - immunology
/ Epitopes
/ Epitopes, T-Lymphocyte - genetics
/ Epitopes, T-Lymphocyte - immunology
/ Humans
/ Mutation
/ Omicron
/ Peptides
/ Proteins
/ Severe acute respiratory syndrome coronavirus 2
/ Spike Glycoprotein, Coronavirus - genetics
/ Spike Glycoprotein, Coronavirus - immunology
/ Vaccines
/ variants
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