Asset Details
Do you wish to reserve the book?
Interplay of mitochondrial metabolism and microRNAs
Hey, we have placed the reservation for you!
By the way, why not check out events that you can attend while you pick your title.
Oops! Something went wrong.
Looks like we were not able to place the reservation. Kindly try again later.
Are you sure you want to remove the book from the shelf?
Interplay of mitochondrial metabolism and microRNAs
Do you wish to request the book?
Interplay of mitochondrial metabolism and microRNAs
Please be aware that the book you have requested cannot be checked out. If you would like to checkout this book, you can reserve another copy
We have requested the book for you!
Your request is successful and it will be processed during the Library working hours. Please check the status of your request in My Requests.
Oops! Something went wrong.
Looks like we were not able to place your request. Kindly try again later.
Journal Article
Interplay of mitochondrial metabolism and microRNAs
2017
Overview
Mitochondria are important organelles in cellular metabolism. Several crucial metabolic pathways such as the energy producing electron transport chain or the tricarboxylic acid cycle are hosted inside the mitochondria. The proper function of mitochondria depends on the import of proteins, which are encoded in the nucleus and synthesized in the cytosol. Micro-ribonucleic acids (miRNAs) are short non-coding ribonucleic acid (RNA) molecules with the ability to prevent messenger RNA (mRNA)-translation or to induce the degradation of mRNA-transcripts. Although miRNAs are mainly located in the cytosol or the nucleus, a subset of ~150 different miRNAs, called mitomiRs, has also been found localized to mitochondrial fractions of cells and tissues together with the subunits of the RNA-induced silencing complex (RISC); the protein complex through which miRNAs normally act to prevent translation of their mRNA-targets. The focus of this review is on miRNAs and mitomiRs with influence on mitochondrial metabolism and their possible pathophysiological impact.
Publisher
Springer International Publishing,Springer Nature B.V
Subject
/ Analysis
/ Animals
/ Biomedical and Life Sciences
/ Cytosol
/ energy
/ Humans
/ microRNA
/ miRNA
/ Nonsense Mediated mRNA Decay
/ Proteins
/ Review
/ RNA
/ RNA-induced silencing complex
/ RNA-Induced Silencing Complex - analysis
/ RNA-Induced Silencing Complex - genetics
/ RNA-Induced Silencing Complex - metabolism
/ Studies
/ tissues
