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Colonoscopic Polypectomy and Long-Term Prevention of Colorectal-Cancer Deaths
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Colonoscopic Polypectomy and Long-Term Prevention of Colorectal-Cancer Deaths
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Journal Article
Colonoscopic Polypectomy and Long-Term Prevention of Colorectal-Cancer Deaths
2012
Overview
On the basis of long-term follow-up data from the National Polyp Study, the authors estimate that mortality from colorectal cancer was about 50% lower among patients who had adenomatous polyps removed than in the general population.
It has been a long-standing belief that screening for colorectal cancer can affect mortality from the disease in two ways: by detecting cancers at an early, curable stage and by detecting and removing adenomas.
1
Detection of early-stage colorectal cancer has been shown to be associated with a reduction in mortality from colorectal cancer in screening trials.
2
–
4
However, an adenomatous polyp is a much more common neoplastic finding on endoscopic screening. We previously reported that colonoscopic polypectomy in the National Polyp Study (NPS) cohort reduced the incidence of colorectal cancer.
5
An important question is whether the cancers prevented by colonoscopic . . .
Publisher
Massachusetts Medical Society
Subject
/ Adenoma - prevention & control
/ Adenomatous Polyps - surgery
/ Aged
/ Biological and medical sciences
/ Colon
/ Colorectal Neoplasms - mortality
/ Colorectal Neoplasms - prevention & control
/ Colorectal Neoplasms - surgery
/ Death
/ Feces
/ Female
/ Humans
/ Investigative techniques, diagnostic techniques (general aspects)
/ Male
/ Polyps
/ Public health. Hygiene-occupational medicine
/ Tumors
