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Relative sit-to-stand power cut-off points and their association with negatives outcomes in older adults
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Relative sit-to-stand power cut-off points and their association with negatives outcomes in older adults
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Journal Article
Relative sit-to-stand power cut-off points and their association with negatives outcomes in older adults
2021
Overview
The purposes of this study were: (i) to evaluate the association of sit-to-stand (STS) power and body composition parameters [body mass index (BMI) and legs skeletal muscle index (SMI)] with age; (ii) to provide cut-off points for low relative STS power (STS
rel
), (iii) to provide normative data for well-functioning older adults and (iv) to assess the association of low STS
rel
with negative outcomes. Cross-sectional design (1369 older adults). STS power parameters assessed by validated equations, BMI and Legs SMI assessed by dual-energy X-ray absorptiometry were recorded. Sex- and age-adjusted segmented and logistic regression analyses and receiver operator characteristic curves were used. Among men, STS
rel
showed a negative association with age up to the age of 85 years (− 1.2 to − 1.4%
year−1
;
p
< 0.05). In women, a negative association with age was observed throughout the old adult life (− 1.2 to − 2.0%
year−1
;
p
< 0.001). Cut-off values for low STS
rel
were 2.5 W kg
−1
in men and 1.9 W kg
−1
in women. Low STS
rel
was associated with frailty (OR [95% CI] = 5.6 [3.1, 10.1]) and low habitual gait speed (HGS) (OR [95% CI] = 2.7 [1.8, 3.9]) in men while low STS
rel
was associated with frailty (OR [95% CI] = 6.9 [4.5, 10.5]) low HGS (OR [95% CI] = 2.9 [2.0, 4.1]), disability in activities of daily living (OR [95% CI] = 2.1 [1.4, 3.2]), and low quality of life (OR [95%CI] = 1.7 [1.2, 2.4]) in women. STS
rel
declined with increasing age in both men and women. Due to the adverse outcomes related to STS
rel
, the reported cut-off points can be used as a clinical tool to identify low STS
rel
among older adults.
Publisher
Nature Publishing Group UK,Nature Publishing Group,Nature Portfolio
Subject
