Journal Article

Key considerations to reduce or address respondent burden in patient-reported outcome (PRO) data collection

Kamudoni, Paul, Roydhouse, Jessica, Schache, Peter, Wilson, Roger, Stephens, Richard, Calvert, Melanie, Rivera, Samantha Cruz, Aiyegbusi, Olalekan Lee

2022

Overview

Patient-reported outcomes (PROs) are used in clinical trials to provide evidence of the benefits and risks of interventions from a patient perspective and to inform regulatory decisions and health policy. The collection of PROs in routine practice can facilitate monitoring of patient symptoms; identification of unmet needs; prioritisation and/or tailoring of treatment to the needs of individual patients and inform value-based healthcare initiatives. However, respondent burden needs to be carefully considered and addressed to avoid high rates of missing data and poor reporting of PRO results, which may lead to poor quality data for regulatory decision making and/or clinical care. The collection of patient-reported outcomes (PROs) may capture patients’ assessments of their health status. Here authors highlight PRO-specific issues that should be considered to minimise respondent burden in clinical trials and routine care.

• Publisher: Nature Publishing Group UK,Nature Publishing Group,Nature Portfolio
• Subject: 692/308/2779 / 692/308/409 / 692/700/784 / Cancer therapies / Clinical outcomes / Clinical trials / Cognitive ability / Data Collection / Decision making / Delivery of Health Care / Health care / Health Policy / Humanities and Social Sciences / Humans / Literacy / Medical research / Missing data / multidisciplinary / Patient Reported Outcome Measures / Patients / Perspective / Prostate cancer / Questionnaires / Science / Science (multidisciplinary)