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Using high-resolution contact networks to evaluate SARS-CoV-2 transmission and control in large-scale multi-day events
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Using high-resolution contact networks to evaluate SARS-CoV-2 transmission and control in large-scale multi-day events
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Journal Article
Using high-resolution contact networks to evaluate SARS-CoV-2 transmission and control in large-scale multi-day events
2022
Overview
The emergence of highly transmissible SARS-CoV-2 variants has created a need to reassess the risk posed by increasing social contacts as countries resume pre-pandemic activities, particularly in the context of resuming large-scale events over multiple days. To examine how social contacts formed in different activity settings influences interventions required to control Delta variant outbreaks, we collected high-resolution data on contacts among passengers and crew on cruise ships and combined the data with network transmission models. We found passengers had a median of 20 (IQR 10–36) unique close contacts per day, and over 60% of their contact episodes were made in dining or sports areas where mask wearing is typically limited. In simulated outbreaks, we found that vaccination coverage and rapid antigen tests had a larger effect than mask mandates alone, indicating the importance of combined interventions against Delta to reduce event risk in the vaccine era.
Here, the authors simulate COVID-19 outbreaks on an empirical contact network derived from digital contact data collected on cruise ships. They model impacts of different control measures and find that combinations of measures, particularly vaccination and rapid antigen testing, are important for mitigating outbreaks.
Publisher
Nature Publishing Group UK,Nature Publishing Group,Nature Portfolio
