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Green synthesis of bimetallic ZnO–CuO nanoparticles and their cytotoxicity properties
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Green synthesis of bimetallic ZnO–CuO nanoparticles and their cytotoxicity properties
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Journal Article
Green synthesis of bimetallic ZnO–CuO nanoparticles and their cytotoxicity properties
2021
Overview
In this study, a simple and green strategy was reported to prepare bimetallic nanoparticles (NPs) by the combination of zinc oxide (ZnO) and copper oxide (CuO) using
Sambucus nigra
L. extract. The physicochemical properties of these NPs such as crystal structure, size, and morphology were studied by X-ray diffraction (XRD), field emission gun scanning electron microscopy (FEG-SEM), and transmission electron microscopy (TEM). The results suggested that these NPs contained polygonal ZnO NPs with hexagonal phase and spherical CuO NPs with monoclinic phase. The anticancer activity of the prepared bimetallic NPs was evaluated against lung and human melanoma cell lines based on MTT assay. As a result, the bimetallic ZnO/CuO NPs exhibited high toxicity on melanoma cancer cells while their toxicity on lung cancer cells was low.
Publisher
Nature Publishing Group UK,Nature Publishing Group,Nature Portfolio
Subject
/ 631/61
/ 631/92
/ Anti-Bacterial Agents - chemistry
/ Anti-Bacterial Agents - pharmacology
/ Green Chemistry Technology - methods
/ Humanities and Social Sciences
/ Humans
/ Melanoma
/ Metal Nanoparticles - chemistry
/ Microbial Sensitivity Tests - methods
/ Microscopy, Electron, Transmission - methods
/ Plant Extracts - pharmacology
/ Scanning electron microscopy
/ Science
/ Spectroscopy, Fourier Transform Infrared - methods
