Journal Article

Molecular structure analyses suggest strategies to therapeutically target SARS-CoV-2

Kutateladze, Tatiana G., Zhang, Yi

2020

Overview

Amid the COVID-19 pandemic, scientists around the globe have been working resolutely to find therapies to treat patients and avert the spreading of the SARS-CoV-2 virus. In this commentary, we highlight some of the latest studies that provide atomic-resolution structural details imperative for the development of vaccines and antiviral therapeutics.

• Publisher: Nature Publishing Group UK,Nature Publishing Group,Nature Portfolio
• Subject: 101/28 / 631/535 / 631/535/1258 / 631/535/1266 / 692/699 / Angiotensin-Converting Enzyme 2 / Antiviral Agents - chemistry / Antiviral Agents - therapeutic use / Antiviral drugs / Betacoronavirus - chemistry / Betacoronavirus - drug effects / Betacoronavirus - immunology / Betacoronavirus - metabolism / Comment / Coronavirus 3C Proteases / Coronavirus Infections - drug therapy / Coronavirus Infections - prevention & control / Coronavirus Infections - therapy / Coronavirus Infections - virology / COVID-19 / COVID-19 Vaccines / Cysteine Endopeptidases - chemistry / Cysteine Endopeptidases - metabolism / Humanities and Social Sciences / Humans / Models, Molecular / Molecular structure / multidisciplinary / Pandemics / Pandemics - prevention & control / Peptidyl-Dipeptidase A - chemistry / Peptidyl-Dipeptidase A - metabolism / Pneumonia, Viral - drug therapy / Pneumonia, Viral - prevention & control / Pneumonia, Viral - therapy / Pneumonia, Viral - virology / SARS-CoV-2 / Science / Science (multidisciplinary) / Severe acute respiratory syndrome coronavirus 2 / Spike Glycoprotein, Coronavirus - chemistry / Spike Glycoprotein, Coronavirus - immunology / Vaccines / Viral diseases / Viral Nonstructural Proteins - chemistry / Viral Nonstructural Proteins - metabolism / Viral Vaccines - chemistry / Viral Vaccines - therapeutic use / Viruses