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Attention-guided deep learning for gestational age prediction using fetal brain MRI
by
Dahmoush, Hisham
, Chueh, Jane
, Lai, Lillian M.
, Lee, Edward H.
, Shen, Liyue
, Oztekin, Ozgur
, Pauly, John M.
, Shpanskaya, Katie
, Guimaraes, Carolina V.
, Lu, Quin
, Mitchell, Courtney
, Halabi, Safwan S.
, Yeom, Kristen W.
, Plasto, Dinko
, McKenna, Emily S.
, Atluri, Mahesh G.
, Zheng, Jimmy
, Kline-Fath, Beth M.
, Xing, Lei
in
631/114/1305
/ 692/308/3187
/ 692/700/1421/65
/ Age
/ Age determination
/ Brain - diagnostic imaging
/ Brain - growth & development
/ Correlation coefficient
/ Datasets as Topic
/ Deep Learning
/ Female
/ Fetus
/ Fetuses
/ Gestational Age
/ Humanities and Social Sciences
/ Humans
/ Image Processing, Computer-Assisted - statistics & numerical data
/ Magnetic resonance imaging
/ Magnetic Resonance Imaging - methods
/ Magnetic Resonance Imaging - standards
/ multidisciplinary
/ Neural networks
/ Neuroimaging
/ Neuroimaging - methods
/ Neuroimaging - standards
/ Pregnancy
/ Pregnancy Trimesters - physiology
/ Science
/ Science (multidisciplinary)
/ Turkey
/ United States
2022
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Attention-guided deep learning for gestational age prediction using fetal brain MRI
by
Dahmoush, Hisham
, Chueh, Jane
, Lai, Lillian M.
, Lee, Edward H.
, Shen, Liyue
, Oztekin, Ozgur
, Pauly, John M.
, Shpanskaya, Katie
, Guimaraes, Carolina V.
, Lu, Quin
, Mitchell, Courtney
, Halabi, Safwan S.
, Yeom, Kristen W.
, Plasto, Dinko
, McKenna, Emily S.
, Atluri, Mahesh G.
, Zheng, Jimmy
, Kline-Fath, Beth M.
, Xing, Lei
in
631/114/1305
/ 692/308/3187
/ 692/700/1421/65
/ Age
/ Age determination
/ Brain - diagnostic imaging
/ Brain - growth & development
/ Correlation coefficient
/ Datasets as Topic
/ Deep Learning
/ Female
/ Fetus
/ Fetuses
/ Gestational Age
/ Humanities and Social Sciences
/ Humans
/ Image Processing, Computer-Assisted - statistics & numerical data
/ Magnetic resonance imaging
/ Magnetic Resonance Imaging - methods
/ Magnetic Resonance Imaging - standards
/ multidisciplinary
/ Neural networks
/ Neuroimaging
/ Neuroimaging - methods
/ Neuroimaging - standards
/ Pregnancy
/ Pregnancy Trimesters - physiology
/ Science
/ Science (multidisciplinary)
/ Turkey
/ United States
2022
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Attention-guided deep learning for gestational age prediction using fetal brain MRI
by
Dahmoush, Hisham
, Chueh, Jane
, Lai, Lillian M.
, Lee, Edward H.
, Shen, Liyue
, Oztekin, Ozgur
, Pauly, John M.
, Shpanskaya, Katie
, Guimaraes, Carolina V.
, Lu, Quin
, Mitchell, Courtney
, Halabi, Safwan S.
, Yeom, Kristen W.
, Plasto, Dinko
, McKenna, Emily S.
, Atluri, Mahesh G.
, Zheng, Jimmy
, Kline-Fath, Beth M.
, Xing, Lei
in
631/114/1305
/ 692/308/3187
/ 692/700/1421/65
/ Age
/ Age determination
/ Brain - diagnostic imaging
/ Brain - growth & development
/ Correlation coefficient
/ Datasets as Topic
/ Deep Learning
/ Female
/ Fetus
/ Fetuses
/ Gestational Age
/ Humanities and Social Sciences
/ Humans
/ Image Processing, Computer-Assisted - statistics & numerical data
/ Magnetic resonance imaging
/ Magnetic Resonance Imaging - methods
/ Magnetic Resonance Imaging - standards
/ multidisciplinary
/ Neural networks
/ Neuroimaging
/ Neuroimaging - methods
/ Neuroimaging - standards
/ Pregnancy
/ Pregnancy Trimesters - physiology
/ Science
/ Science (multidisciplinary)
/ Turkey
/ United States
2022
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Attention-guided deep learning for gestational age prediction using fetal brain MRI
Journal Article
Attention-guided deep learning for gestational age prediction using fetal brain MRI
2022
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Overview
Magnetic resonance imaging offers unrivaled visualization of the fetal brain, forming the basis for establishing age-specific morphologic milestones. However, gauging age-appropriate neural development remains a difficult task due to the constantly changing appearance of the fetal brain, variable image quality, and frequent motion artifacts. Here we present an end-to-end, attention-guided deep learning model that predicts gestational age with R
2
score of 0.945, mean absolute error of 6.7 days, and concordance correlation coefficient of 0.970. The convolutional neural network was trained on a heterogeneous dataset of 741 developmentally normal fetal brain images ranging from 19 to 39 weeks in gestational age. We also demonstrate model performance and generalizability using independent datasets from four academic institutions across the U.S. and Turkey with R
2
scores of 0.81–0.90 after minimal fine-tuning. The proposed regression algorithm provides an automated machine-enabled tool with the potential to better characterize in utero neurodevelopment and guide real-time gestational age estimation after the first trimester.
Publisher
Nature Publishing Group UK,Nature Publishing Group,Nature Portfolio
Subject
/ Age
/ Brain - growth & development
/ Female
/ Fetus
/ Fetuses
/ Humanities and Social Sciences
/ Humans
/ Image Processing, Computer-Assisted - statistics & numerical data
/ Magnetic Resonance Imaging - methods
/ Magnetic Resonance Imaging - standards
/ Pregnancy Trimesters - physiology
/ Science
/ Turkey
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