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Myocardial Viability and Survival in Ischemic Left Ventricular Dysfunction

by Pellikka, Patricia A , Jones, Robert H , Berman, Daniel S , Farsky, Pedro S , Michler, Robert E , Maurer, Gerald , Lee, Kerry L , Holly, Thomas A , Drozdz, Jaroslaw , Nicolau, Jose C , Panza, Julio A , Binkley, Philip F , Velazquez, Eric J , Asch, Federico M , Favaloro, Liliana E , Doenst, Torsten , Bonow, Robert O , She, Lilin , Feldman, Arthur M , Alotti, Nasri , Desvigne-Nickens, Patrice , Wrobel, Krzysztof

in Aged / Cardiovascular disease / Cardiovascular Diseases - mortality / Combined Modality Therapy / Coronary Artery Bypass / Coronary Artery Disease - complications / Coronary Artery Disease - drug therapy / Coronary Artery Disease - surgery / Coronary vessels / Echocardiography, Stress / Female / Follow-Up Studies / Heart attacks / Heart Failure - drug therapy / Heart Failure - etiology / Heart Failure - surgery / Humans / Hypotheses / Kaplan-Meier Estimate / Male / Middle Aged / Myocardial Ischemia / Myocardium - pathology / Patients / Proportional Hazards Models / Statistics, Nonparametric / Studies / Tomography, Emission-Computed, Single-Photon / Ventricular Dysfunction, Left - drug therapy / Ventricular Dysfunction, Left - etiology / Ventricular Dysfunction, Left - surgery

2011

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Myocardial Viability and Survival in Ischemic Left Ventricular Dysfunction

2011

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2011

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Journal Article

Myocardial Viability and Survival in Ischemic Left Ventricular Dysfunction

Pellikka, Patricia A,

Jones, Robert H,

Berman, Daniel S,

Farsky, Pedro S,

Michler, Robert E,

Maurer, Gerald,

Lee, Kerry L,

Holly, Thomas A,

Drozdz, Jaroslaw,

Nicolau, Jose C,

Panza, Julio A,

Binkley, Philip F,

Velazquez, Eric J,

Asch, Federico M,

Favaloro, Liliana E,

Doenst, Torsten,

Bonow, Robert O,

She, Lilin,

Feldman, Arthur M,

Alotti, Nasri,

Desvigne-Nickens, Patrice,

Wrobel, Krzysztof

2011

Overview

Patients with CAD and LV dysfunction were assigned to receive either medical therapy alone or medical therapy plus CABG. There was no evidence of significant interaction between myocardial viability and treatment assignment. Coronary artery disease is an important contributor to the rise in the prevalence of heart failure and in associated mortality and morbidity. 1 – 4 It has not been clearly established whether coronary-artery bypass grafting (CABG) has a role in improving the symptoms and the rate of survival of patients with coronary artery disease and heart failure. We conducted the multicenter Surgical Treatment for Ischemic Heart Failure (STICH) trial 5 , 6 to examine two hypotheses, one of which (hypothesis 1) compared the efficacy of medical therapy alone with that of medical therapy plus CABG in patients with coronary artery disease and left ventricular . . .

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Publisher

Massachusetts Medical Society

Subject

Aged

/ Cardiovascular disease

/ Cardiovascular Diseases - mortality

/ Combined Modality Therapy

/ Coronary Artery Bypass

/ Coronary Artery Disease - complications

/ Coronary Artery Disease - drug therapy