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The prescription of beta-blockers in older patients with heart failure with reduced ejection fraction: an observational study in Vietnam
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The prescription of beta-blockers in older patients with heart failure with reduced ejection fraction: an observational study in Vietnam
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Journal Article
The prescription of beta-blockers in older patients with heart failure with reduced ejection fraction: an observational study in Vietnam
2024
Overview
This study in older hospitalized patients with heart failure with reduced ejection fraction (HFrEF) aimed to examine the prevalence of beta-blocker prescription and its associated factors. A total of 190 participants were recruited from July 2019 to July 2020. The inclusion criteria included: (1) aged ≥ 60 years, (2) having a diagnosis of chronic HFrEF in the medical records, (3) hospitalized for at least 48 h. The participants had a mean age of 75.5 ± 9.1, and 46.8% were female. Of these, 55.3% were prescribed beta-blockers during admission. To explore the factors associated with beta-blocker prescription, multivariable logistic regression analysis was applied and the results were presented as odds ratios (OR) and 95% confidence intervals (CI). On multivariate logistic regression models, higher NYHA classes (OR 0.49, 95%CI 0.26–0.94), chronic obstructive pulmonary disease (OR 0.17, 95% CI 0.04–0.85), chronic kidney disease (OR 0.40, 95% CI 0.19–0.83), and heart rate under 65 (OR 0.34, 95% CI 0.12–0.98) were associated with a reduced likelihood of prescription. In this study, we found a low rate of beta-blocker prescriptions, with only around half of the participants being prescribed beta-blockers. Further studies are needed to examine the reasons for the under-prescription of beta-blockers, and to evaluate the long-term benefits of beta-blockers in elderly patients with HFrEF in this population.
Publisher
Nature Publishing Group UK,Nature Publishing Group,Nature Portfolio
Subject
/ 692/4019
/ Adrenergic beta-Antagonists - therapeutic use
/ Aged
/ Chronic obstructive pulmonary disease
/ Drug Prescriptions - statistics & numerical data
/ Female
/ Heart Failure - drug therapy
/ Heart Failure - physiopathology
/ Hospitalization - statistics & numerical data
/ Humanities and Social Sciences
/ Humans
/ Male
/ Pulmonary Disease, Chronic Obstructive - drug therapy
/ Pulmonary Disease, Chronic Obstructive - physiopathology
/ Science
