Asset Details
Do you wish to reserve the book?
Lessons learned from 12 years using the Woven Endobridge for the treatment of cerebral aneurysms in a multi-center series
Hey, we have placed the reservation for you!
By the way, why not check out events that you can attend while you pick your title.
Oops! Something went wrong.
Looks like we were not able to place the reservation. Kindly try again later.
Are you sure you want to remove the book from the shelf?
Lessons learned from 12 years using the Woven Endobridge for the treatment of cerebral aneurysms in a multi-center series
Do you wish to request the book?
Lessons learned from 12 years using the Woven Endobridge for the treatment of cerebral aneurysms in a multi-center series
Please be aware that the book you have requested cannot be checked out. If you would like to checkout this book, you can reserve another copy
We have requested the book for you!
Your request is successful and it will be processed during the Library working hours. Please check the status of your request in My Requests.
Oops! Something went wrong.
Looks like we were not able to place your request. Kindly try again later.
Journal Article
Lessons learned from 12 years using the Woven Endobridge for the treatment of cerebral aneurysms in a multi-center series
2024
Overview
Intrasaccular flow disruption with the Woven Endobridge (WEB) has become a well-established endovascular technique for the treatment of intracranial aneurysms. This study presents our 12-year experience with the WEB and evaluates its evolving indications, procedures, and outcomes. A consecutive series of 324 aneurysms treated with WEB between 2011 and 2023 at three neurovascular centers was retrospectively analyzed and the study group was divided into four treatment periods. Uni- and multivariate analyses were performed to evaluate factors associated with technical success, thromboembolic complications, and angiographic outcome. The mean aneurysm size was 7.0 ± 3.6 mm and decreased during the study period, while the proportion of atypical sites for WEB implantation increased. WEB implantation was technically successful in 96.0%, and the ratio of WEB width to dome width increased during the study period, indicating oversizing. The neurological complication rate was 4.9% (1.5% major, 3.4% minor) and the mid-term complete occlusion rate was 60.6% (81.9% adequate occlusion), with no statistical differences in either outcome measure between the study periods. In multivariate analyses, the use of WEB 17 was associated with increased technical success (HR: 7.4, 95%CI: 2.4-23.6,
p
<0.01), whereas ruptured aneurysm status (HR: 2.5, 95%CI: 1.0-6.0,
p
=0.04) and the use of additional stents (HR: 4.8, 95%CI: 1.6-14.4,
p
<0.01) predicted thromboembolic complications. Appropriate oversizing of the WEB favored mid-term complete occlusion (HR: 10.5, 95%CI: 1.3-83.3,
p
=0.03). The results suggest an expansion of the indications for WEB implantation and highlight the importance of oversizing for treatment efficacy.
Publisher
Nature Publishing Group UK,Nature Publishing Group,Nature Portfolio
Subject
