Asset Details
Do you wish to reserve the book?
Screening of lactic acid bacteria with anti-adipogenic effect and potential probiotic properties from grains
Hey, we have placed the reservation for you!
By the way, why not check out events that you can attend while you pick your title.
Oops! Something went wrong.
Looks like we were not able to place the reservation. Kindly try again later.
Are you sure you want to remove the book from the shelf?
Screening of lactic acid bacteria with anti-adipogenic effect and potential probiotic properties from grains
Do you wish to request the book?
Screening of lactic acid bacteria with anti-adipogenic effect and potential probiotic properties from grains
Please be aware that the book you have requested cannot be checked out. If you would like to checkout this book, you can reserve another copy
We have requested the book for you!
Your request is successful and it will be processed during the Library working hours. Please check the status of your request in My Requests.
Oops! Something went wrong.
Looks like we were not able to place your request. Kindly try again later.
Journal Article
Screening of lactic acid bacteria with anti-adipogenic effect and potential probiotic properties from grains
2023
Overview
A total of 187 lactic acid bacteria were isolated from four types of grains collected in South Korea. The bacterial strains were assigned as members of
Levilactobacillus brevis, Latilactobacillus curvatus, Lactiplantibacillus plantarum
,
Lactococcus taiwanensis
,
Pediococcus pentosaceus
, and
Weissella paramesenteroides
based on the closest similarity using 16S rRNA gene sequence analysis. The strains belonging to the same species were analyzed using RAPD-PCR, and one or two among strains showing the same band pattern were selected. Finally, 25 representative strains were selected for further functional study. Inhibitory effects of lipid accumulation were observed in the strains tested.
Pediococcus pentosaceus
K28,
Levilactobacillus brevis
RP21 and
Lactiplantibacillus plantarum
RP12 significantly reduced lipid accumulation and did not show cytotoxicity in C3H10T1/2 cells at treatment of 1–200 μg/mL. The three LAB strains decreased significantly expression of six adipogenic marker genes,
PPARγ
,
C/EBPα
,
CD36
,
LPL
,
FAS
and
ACC
, in C3H10T1/2 adipocytes. The three strains survived under strong acidity and bile salt conditions. The three strains showed adhesion to Caco-2 cells similar to a reference strain LGG. The resistance of the three strains to several antibiotics was also assessed. Strains RP12 and K28 were confirmed not to produce harmful enzymes based on API ZYM kit results. Based on these results, strains K28, RP21 and RP12 isolated from grains had the ability to inhibit adipogenesis in adipocytes and potentially be useful as probiotics.
Publisher
Nature Publishing Group UK,Nature Publishing Group,Nature Portfolio
Subject
/ 631/61
/ 692/700
/ Acidity
/ Bacteria
/ Humanities and Social Sciences
/ Humans
/ Lactiplantibacillus plantarum
/ Lactobacillales - metabolism
/ Lipids
/ Pediococcus pentosaceus - genetics
/ Random Amplified Polymorphic DNA Technique
/ RNA, Ribosomal, 16S - genetics
/ RNA, Ribosomal, 16S - metabolism
/ rRNA 16S
/ Science
