Journal Article

Tumor-like conditions that mimic liver tumors

Salem, Usama, Diab, Mahmoud, Stanietzky, Nir, Menias, Christine O., Klimkowski, Sergio, Elsayes, Khaled M., Fraivillig, Kurt, Rezvani, Maryam, Salem, Ahmed Ebada, Naik, Sagar, Shaaban, Akram M.

2025

Overview

Non-neoplastic tumor-like conditions of the liver can appear similar to hepatic neoplasms. In many cases, a biopsy is required to confirm the pathology. However, several tumor-like conditions can be correctly diagnosed or suggested prospectively, thus saving patients from unnecessary anxiety and expense. In this image-focused review, we present the ultrasound, computed tomography, magnetic resonance imaging, and positron emission tomography scan features of eight such entities. Clues that indicate the correct pathology are discussed, and the usual clinical setting is described. Many of these lesions are treated differently from true neoplasms, and the current treatment plan is discussed in many of the cases presented. After reviewing this article, the reader will have a better understanding of these lesions and the situations in which they should be included in the differential diagnosis.

• Publisher: Galenos Yayinevi Tic. Ltd,Galenos Publishing House,Galenos Publishing,Turkish Society of Radiology
• Subject: Abdomen / Abdominal Imaging - Invited Review / benign hepatic lesion / Biopsy / Care and treatment / Cholangitis / Computed tomography / Congenital diseases / Diagnosis / Diagnosis, Differential / Epstein-Barr virus / Female / hepatic amyloidosis / hepatic extramedullary hematopoiesis / hepatic pseudotumor / hepatic sarcoidosis / hepatic tumor mimics / hepatic tumor-like conditions / hepatobiliary tuberculomas / Humans / Lesions / Liver / Liver - diagnostic imaging / Liver - pathology / Liver Diseases - diagnosis / Liver Diseases - diagnostic imaging / Liver Diseases - pathology / liver imaging / Liver Neoplasms - diagnosis / Liver Neoplasms - diagnostic imaging / Liver Neoplasms - pathology / Liver tumors / Magnetic resonance imaging / Magnetic Resonance Imaging - methods / Male / Medical research / Medicine, Experimental / mesenchymal hamartoma / Middle Aged / myofibroblastoma / Necrosis / Neoplasms / Pathology / Pediatrics / peliosis hepatis / Physiological aspects / Positron emission / Positron-Emission Tomography - methods / Smooth muscle / Tomography, X-Ray Computed - methods / Transplants & implants / Tuberculosis / Tumors / Ultrasonic imaging / Ultrasonography - methods