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A comparative review of human milk banking and national tissue banking programs
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A comparative review of human milk banking and national tissue banking programs
A comparative review of human milk banking and national tissue banking programs
Journal Article

A comparative review of human milk banking and national tissue banking programs

2024
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Overview
This paper explores the legislative and operational commonalities and differences in Medical Products of Human Origin (MPHO) programs, including blood, hematopoietic cells, tissues and reproductive cells and human milk banking. The analysis includes ethical principles in donation and utilization, policies and legislation, public awareness and education, registries, guidelines in donor selection, safety and quality assurance, operational models and funding, infrastructure and human resources and biovigilance and evaluation of outcomes. Unlike other MPHO, the need for donor human milk (DHM) may be greatly reduced, that is, by ensuring optimal support for maternal lactation and breastfeeding. This should not be lost in the drive for wider and improved service provision. Nevertheless, increased overall demand for DHM is expected as a result of forthcoming international recommendations and also its increased use as the first‐choice supplement to a mother's own milk both within and beyond preterm, low‐birthweight and sick infant populations. Insight into current human milk banking highlights differences and gaps in practices that can benefit from further exploration and harmonization. Strong similarities with the ethical and operational principles underpinning donation and processing of the diverse MPHO suggest that legislating human milk banks within similar MPHO frameworks may bring additional safety and facilitate improved product quality. Moreover, that MPHO‐inspired models operating within attainable regulatory requirements may contribute to sustainable human milk banking activity and growth. Key messages The strong similarities with the ethical, quality and safety expectations underpinning the donation and processing of the diverse Medical Products of Human Origin (MPHO) can be harnessed to provide additional safety levels and improved donor human milk (DHM) quality. MPHO‐inspired models operating within attainable regulatory requirements may contribute to sustainable human milk banking activity and growth. The need for DHM may be greatly reduced through optimal support for maternal lactation and breastfeeding Current global milk banking practices can benefit from expanded and harmonized, international guidance.