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Epidemiology of readmissions in early infancy following nonelective cesarean delivery

by Merin, Lee Ann , Potthoff, Kim , Szychowski, Jeff M , Varner, Michael , Hutchison, M , Cleary, Kirsten , Servay Christine , Longo, Sherri , Owens, Michelle , Lofland, Elaine , Godbold Ester , Boggess, Kim A , Ta Vu , LeDuke Rachel , Grant Janatha , Hofer, Melissa , Dorman, Karen , Esplin, Sean , Rahman Zhara , Quinn, Rebecca , Timothy, Suzanne , Beamon, Carmen , Salmon, Shanna , Redd Winter , Ehsani Masoomeh , Nunley, Michael , Tran, Sa , Wong, Christine , Huaracha Virginia , Ortiz, Felecia , Andrews, William , Behunin Amanda , Eng, Connie , Wallace Kedra , Martin, James N , Orange Yukiko Nakamura , George, Michael , Sowles Amber , Garcia, Lisa , Pope, Sue , Adam, Gloria , Blackwell, Sean , Recabarren Cecelia , Mailhot, Richard , Manor, Linda , Johnson, Vanessa , Tew Marci , Pandya, Pat , Dellerman Sandi , Jauk Victoria , Ambalavanan Namasivayam , Kellett, Letson , Cliver, Sue , Ogletree, Richard , Tamhane Ashutosh , Morgan, Beth , Givens, Paula , Conley, Barbara , Saade, George , Aguillon Brenda , Tita, Alan T , Wilson-Jimenez, Maria , Torres, Caroline , Parks, Christopher , Steele, Robin , Bahena, Maria , Hill, Kim , Cox, Richard , Wapner, Ronald

in Antibiotics / Apnea / Azithromycin / Cesarean section / Epidemiology / Ethnicity / Infants / Microbiomes / Minority & ethnic groups / Neonates / Postpartum / Prophylaxis / Risk analysis / Risk factors / Secondary analysis / Sepsis / Small for gestational age / Steroid hormones / Steroids

2021

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Epidemiology of readmissions in early infancy following nonelective cesarean delivery

2021

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2021

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Journal Article

Epidemiology of readmissions in early infancy following nonelective cesarean delivery

Merin, Lee Ann,

Potthoff, Kim,

Szychowski, Jeff M,

Varner, Michael,

Hutchison, M,

Cleary, Kirsten,

Servay Christine,

Longo, Sherri,

Owens, Michelle,

Lofland, Elaine,

Godbold Ester,

Boggess, Kim A,

Ta Vu,

LeDuke Rachel,

Grant Janatha,

Hofer, Melissa,

Dorman, Karen,

Esplin, Sean,

Rahman Zhara,

Quinn, Rebecca,

Timothy, Suzanne,

Beamon, Carmen,

Salmon, Shanna,

Redd Winter,

Ehsani Masoomeh,

Nunley, Michael,

Tran, Sa,

Wong, Christine,

Huaracha Virginia,

Ortiz, Felecia,

Andrews, William,

Behunin Amanda,

Eng, Connie,

Wallace Kedra,

Martin, James N,

Orange Yukiko Nakamura,

George, Michael,

Sowles Amber,

Garcia, Lisa,

Pope, Sue,

Adam, Gloria,

Blackwell, Sean,

Recabarren Cecelia,

Mailhot, Richard,

Manor, Linda,

Johnson, Vanessa,

Tew Marci,

Pandya, Pat,

Dellerman Sandi,

Jauk Victoria,

Ambalavanan Namasivayam,

Kellett, Letson,

Cliver, Sue,

Ogletree, Richard,

Tamhane Ashutosh,

Morgan, Beth,

Givens, Paula,

Conley, Barbara,

Saade, George,

Aguillon Brenda,

Tita, Alan T,

Wilson-Jimenez, Maria,

Torres, Caroline,

Parks, Christopher,

Steele, Robin,

Bahena, Maria,

Hill, Kim,

Cox, Richard,

Wapner, Ronald

2021

Overview

ObjectiveDetermine incidence and risk factors for readmissions in early infancy.Study designSecondary analysis of data from the Cesarean Section Optimal Antibiotic Prophylaxis trial. All unplanned revisits (unplanned clinic, ER visits, and hospital readmissions) and hospital readmissions (initial discharge to 3-month follow-up) were analyzed.Results295 (15.9%) of 1850 infants had revisits with risk factors being ethnicity (adjusted odds ratio (aOR): 0.6 for Hispanic), maternal postpartum antibiotics (1.89), azithromycin treatment (1.22), small for gestational age (1.68), apnea (3.82), and hospital stay after birth >90th percentile (0.49). 71 (3.8%) of 1850 infants were readmitted with risk factors being antenatal steroids (aOR 2.49), elective repeat C/section (0.72), postpartum maternal antibiotics (2.22), O2 requirement after delivery room (2.82), and suspected/proven neonatal sepsis (0.55).Conclusion(s)Multiple risk factors were identified, suggesting potential impact on the neonatal microbiome (maternal postpartum antibiotics) or issues related to access/cost of care (Hispanic ethnicity associated with fewer revisits).

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Publisher

Nature Publishing Group

Subject

/ Apnea

/ Infants