Asset Details
Do you wish to reserve the book?
The implications of silent transmission for the control of COVID-19 outbreaks
Hey, we have placed the reservation for you!
By the way, why not check out events that you can attend while you pick your title.
Oops! Something went wrong.
Looks like we were not able to place the reservation. Kindly try again later.
Are you sure you want to remove the book from the shelf?
The implications of silent transmission for the control of COVID-19 outbreaks
Do you wish to request the book?
The implications of silent transmission for the control of COVID-19 outbreaks
Please be aware that the book you have requested cannot be checked out. If you would like to checkout this book, you can reserve another copy
We have requested the book for you!
Your request is successful and it will be processed during the Library working hours. Please check the status of your request in My Requests.
Oops! Something went wrong.
Looks like we were not able to place your request. Kindly try again later.
Journal Article
The implications of silent transmission for the control of COVID-19 outbreaks
2020
Overview
Since the emergence of coronavirus disease 2019 (COVID-19), unprecedented movement restrictions and social distancing measures have been implemented worldwide. The socioeconomic repercussions have fueled calls to lift these measures. In the absence of population-wide restrictions, isolation of infected individuals is key to curtailing transmission. However, the effectiveness of symptom-based isolation in preventing a resurgence depends on the extent of presymptomatic and asymptomatic transmission. We evaluate the contribution of presymptomatic and asymptomatic transmission based on recent individual-level data regarding infectiousness prior to symptom onset and the asymptomatic proportion among all infections. We found that the majority of incidences may be attributable to silent transmission from a combination of the presymptomatic stage and asymptomatic infections. Consequently, even if all symptomatic cases are isolated, a vast outbreak may nonetheless unfold. We further quantified the effect of isolating silent infections in addition to symptomatic cases, finding that over one-third of silent infections must be isolated to suppress a future outbreak below 1% of the population. Our results indicate that symptom-based isolation must be supplemented by rapid contact tracing and testing that identifies asymptomatic and presymptomatic cases, in order to safely lift current restrictions and minimize the risk of resurgence.
Publisher
National Academy of Sciences
Subject
/ Adult
/ Aged
/ Asymptomatic Infections - epidemiology
/ Betacoronavirus - isolation & purification
/ Child
/ Contact Tracing - statistics & numerical data
/ Coronavirus Infections - epidemiology
/ Coronavirus Infections - prevention & control
/ Coronavirus Infections - transmission
/ Coronavirus Infections - virology
/ COVID-19
/ Female
/ Humans
/ Infant
/ Male
/ Pandemics - prevention & control
/ Pneumonia, Viral - epidemiology
/ Pneumonia, Viral - prevention & control
/ Pneumonia, Viral - transmission
