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Automated velocity mapping of migrating cell populations (AVeMap)
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Automated velocity mapping of migrating cell populations (AVeMap)
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Automated velocity mapping of migrating cell populations (AVeMap)
Automated velocity mapping of migrating cell populations (AVeMap)
Journal Article

Automated velocity mapping of migrating cell populations (AVeMap)

2012
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Overview
This paper presents AVeMap, a method and software for automated analysis of cell migration in dense monolayers. Characterizing the migration of a population of cells remains laborious and somewhat subjective. Advances in genetics and robotics allow researchers to perform many experiments in parallel, but analyzing the large sets of data remains a bottleneck. Here we describe a rapid, fully automated correlation-based method for cell migration analysis, compatible with standard video microscopy. This method allows for the computation of quantitative migration parameters via an extensive dynamic mapping of cell displacements.