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Whole Genome Sequencing Analysis of African Orthobunyavirus Isolates Reveals Naturally Interspecies Segments Recombinations between Bunyamwera and Ngari Viruses
by
Touré, Cheikh Talibouya
, Gladkikh, Anna S.
, Faye, Ousmane
, Faye, Oumar
, Dedkov, Vladimir G.
, Ndiaye, Mignane
, Diagne, Moussa Moïse
, Dieng, Idrissa
, Faye, Babacar
, Dolgova, Anna S.
, Sall, Amadou Alpha
, Mhamadi, Moufid
in
Abortion
/ Analysis
/ Animals
/ Arthropods
/ Brief Report
/ Bunyamwera
/ Bunyamwera orthobunyavirus
/ Bunyamwera virus - genetics
/ Bunyaviruses
/ Coccidioidomycosis
/ Enzymes
/ Fever
/ Genetic aspects
/ Genetic recombination
/ genome
/ Genomes
/ Hemorrhage
/ Hemorrhagic Fever Virus, Crimean-Congo
/ Host range
/ Identification and classification
/ Infectious diseases
/ Orthobunyavirus
/ Orthobunyavirus - genetics
/ Proteins
/ prototypes
/ Public health
/ range improvement
/ Recombination
/ Recombination, Genetic
/ Rift Valley fever
/ Rift Valley fever phlebovirus
/ RNA polymerase
/ RNA viruses
/ segmented RNA
/ serogroup
/ serotypes
/ Software
/ Strains (organisms)
/ Testing
/ Viruses
/ Whole Genome Sequencing
2023
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Whole Genome Sequencing Analysis of African Orthobunyavirus Isolates Reveals Naturally Interspecies Segments Recombinations between Bunyamwera and Ngari Viruses
by
Touré, Cheikh Talibouya
, Gladkikh, Anna S.
, Faye, Ousmane
, Faye, Oumar
, Dedkov, Vladimir G.
, Ndiaye, Mignane
, Diagne, Moussa Moïse
, Dieng, Idrissa
, Faye, Babacar
, Dolgova, Anna S.
, Sall, Amadou Alpha
, Mhamadi, Moufid
in
Abortion
/ Analysis
/ Animals
/ Arthropods
/ Brief Report
/ Bunyamwera
/ Bunyamwera orthobunyavirus
/ Bunyamwera virus - genetics
/ Bunyaviruses
/ Coccidioidomycosis
/ Enzymes
/ Fever
/ Genetic aspects
/ Genetic recombination
/ genome
/ Genomes
/ Hemorrhage
/ Hemorrhagic Fever Virus, Crimean-Congo
/ Host range
/ Identification and classification
/ Infectious diseases
/ Orthobunyavirus
/ Orthobunyavirus - genetics
/ Proteins
/ prototypes
/ Public health
/ range improvement
/ Recombination
/ Recombination, Genetic
/ Rift Valley fever
/ Rift Valley fever phlebovirus
/ RNA polymerase
/ RNA viruses
/ segmented RNA
/ serogroup
/ serotypes
/ Software
/ Strains (organisms)
/ Testing
/ Viruses
/ Whole Genome Sequencing
2023
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Whole Genome Sequencing Analysis of African Orthobunyavirus Isolates Reveals Naturally Interspecies Segments Recombinations between Bunyamwera and Ngari Viruses
by
Touré, Cheikh Talibouya
, Gladkikh, Anna S.
, Faye, Ousmane
, Faye, Oumar
, Dedkov, Vladimir G.
, Ndiaye, Mignane
, Diagne, Moussa Moïse
, Dieng, Idrissa
, Faye, Babacar
, Dolgova, Anna S.
, Sall, Amadou Alpha
, Mhamadi, Moufid
in
Abortion
/ Analysis
/ Animals
/ Arthropods
/ Brief Report
/ Bunyamwera
/ Bunyamwera orthobunyavirus
/ Bunyamwera virus - genetics
/ Bunyaviruses
/ Coccidioidomycosis
/ Enzymes
/ Fever
/ Genetic aspects
/ Genetic recombination
/ genome
/ Genomes
/ Hemorrhage
/ Hemorrhagic Fever Virus, Crimean-Congo
/ Host range
/ Identification and classification
/ Infectious diseases
/ Orthobunyavirus
/ Orthobunyavirus - genetics
/ Proteins
/ prototypes
/ Public health
/ range improvement
/ Recombination
/ Recombination, Genetic
/ Rift Valley fever
/ Rift Valley fever phlebovirus
/ RNA polymerase
/ RNA viruses
/ segmented RNA
/ serogroup
/ serotypes
/ Software
/ Strains (organisms)
/ Testing
/ Viruses
/ Whole Genome Sequencing
2023
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Whole Genome Sequencing Analysis of African Orthobunyavirus Isolates Reveals Naturally Interspecies Segments Recombinations between Bunyamwera and Ngari Viruses
Journal Article
Whole Genome Sequencing Analysis of African Orthobunyavirus Isolates Reveals Naturally Interspecies Segments Recombinations between Bunyamwera and Ngari Viruses
2023
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Overview
Bunyamwera virus is the prototype of the Bunyamwera serogroup, which belongs to the order Bunyavirales of the Orthobunyavirus genus in the Peribunyaviridae family. Bunyamwera is a negative-sense RNA virus composed of three segments S, M, and L. Genetic recombination is possible between members of this order as it is already documented. Additionally, it can lead to pathogenic or host range improvement, if it occurs with viruses of public health and agricultural importance such as Rift Valley fever virus and Crimea–Congo hemorrhagic fever virus. Here, we characterize five African Orthobunyavirus viruses from different geographical regions. Our results suggest that the five newly characterized strains are identified as Bunyamwera virus strains. Furthermore, two of the five strains sequenced in this study are recombinant strains, as fragments of their segments are carried by Ngari and Bunyamwera strains. Further investigations are needed to understand the functional impact of these recombinations.
Publisher
MDPI AG,MDPI
Subject
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