Journal Article

Inferior Parietal Lobe Activity Reveals Bimanual Coupling and Interference

Bove, Marco, Brigadoi, Sabrina, Cutini, Simone, Biggio, Monica, Brichetto, Giampaolo, Iester, Costanza, Bonzano, Laura, Bisio, Ambra

2025

Overview

When humans move both hands simultaneously, bimanual coupling or interference can occur. The circles‐lines paradigm is used to study the bimanual coupling and interference effects: Participants simultaneously draw either lines or circles with both hands (congruent), or draw lines with one hand and circles with the other hand (incongruent condition). Despite extensive behavioral research on bimanual coupling with this paradigm, our knowledge of the neural circuitry involved remains limited. Here, we capitalized on the advantages provided by functional near‐infrared spectroscopy to unveil the neural substrates of bimanual coupling within an ecologically valid experimental setting. Behavioral results confirmed previous literature, showing that the shapes become more oval due to the interference between the hands, causing the circle to resemble a line and vice versa. Additionally, performance in the congruent condition correlated with performance in the incongruent condition. From a neural perspective, we observed greater activity in sensorimotor areas and the right premotor area during the incongruent compared to the congruent condition. A novel temporal analysis of the time course of oxyhemoglobin signals revealed that the right hemisphere reached maximum amplitude before the left during the incongruent condition and revealed differences between conditions in parietal areas, showing that bimanual interference is associated not only with motor areas but also with associative areas. Finally, right inferior parietal lobe activity correlated with bimanual performance, suggesting a role for this area in bimanual tasks when the motor program of one hand is influenced by sensorimotor information from the contralateral hand. Our study demonstrates fNIRS effectiveness in investigating bimanual interference during the circles‐lines paradigm. fNIRS allows correct drawing positions, ensuring ecological validity. Performance in congruent tasks predicts incongruent performance. Time‐course analysis shows parietal differences, with the right hemisphere peaking earlier during the incongruent condition. Right inferior parietal lobe activity correlates with bimanual interference.

• Publisher: John Wiley & Sons, Inc
• Subject: Adult / bimanual coupling / Brain / Brain Mapping / Circuits / Coupling / Electroencephalography / Female / Functional Laterality - physiology / functional near‐infrared spectroscopy / Hand - physiology / Hands / Hemispheric laterality / Humans / Infrared spectroscopy / Male / Medical imaging / motor dual‐task / Near infrared radiation / Neural circuitry / Neural networks / Neuroimaging / Oxyhemoglobin / Oxyhemoglobins - metabolism / parietal cortex / Parietal lobe / Parietal Lobe - physiology / Psychomotor Performance - physiology / Sensorimotor system / Spectroscopy, Near-Infrared / Spectrum analysis / Verbal communication / Young Adult