Asset Details

MbrlCatalogueTitleDetail

Do you wish to reserve the book?

Association between Vitamin D Serum Levels and Immune Response to the BNT162b2 Vaccine for SARS-CoV-2

by Sabrina, Peressini , Klersy, Catherine , Marena, Carlo , Cassaniti, Irene , Cutti, Sara , Grugnetti, Anna Maria , Caccialanza, Riccardo , d’Angelo, Piera , Cereda, Emanuele , Lilleri, Daniele , Albertini, Riccardo , Fausto, Baldanti , Zelini, Paola , Grugnetti, Giuseppina

in 25-Hydroxyvitamin D / Alfacalcidol / Amino acids / Antibodies / Brief Report / Calcifediol / Coronaviruses / COVID-19 vaccines / Cytokines / Health aspects / Immune response / Immunoglobulin G / Infections / Influenza / Lymphocytes T / Medical personnel / Micronutrients / mRNA / SARS-CoV-2 / Serum levels / Severe acute respiratory syndrome coronavirus 2 / vaccine / Vaccines / Vitamin D

2022

Yes Please

Hey, we have placed the reservation for you!

By the way, why not check out events that you can attend while you pick your title.

Oops! Something went wrong.

Looks like we were not able to place the reservation. Kindly try again later.

Are you sure you want to remove the book from the shelf?

Association between Vitamin D Serum Levels and Immune Response to the BNT162b2 Vaccine for SARS-CoV-2

2022

Confirm

Do you wish to request the book?

Association between Vitamin D Serum Levels and Immune Response to the BNT162b2 Vaccine for SARS-CoV-2

2022

Please be aware that the book you have requested cannot be checked out. If you would like to checkout this book, you can reserve another copy

How would you like to get it?

Submit

We have requested the book for you!

Your request is successful and it will be processed during the Library working hours. Please check the status of your request in My Requests.

Oops! Something went wrong.

Looks like we were not able to place your request. Kindly try again later.

Journal Article

Association between Vitamin D Serum Levels and Immune Response to the BNT162b2 Vaccine for SARS-CoV-2

Sabrina, Peressini,

Klersy, Catherine,

Marena, Carlo,

Cassaniti, Irene,

Cutti, Sara,

Grugnetti, Anna Maria,

Caccialanza, Riccardo,

d’Angelo, Piera,

Cereda, Emanuele,

Lilleri, Daniele,

Albertini, Riccardo,

Fausto, Baldanti,

Zelini, Paola,

Grugnetti, Giuseppina

2022

Overview

The use of micronutrients such as vitamin D could improve the response to viral vaccines, particularly in immunosuppressed and immunosenescent subjects. Here, we analysed the association between serum 25-hydroxyvitamin D (25OHD) levels and the immune response elicited by the BNT162b2 vaccine in a cohort of 101 healthcare workers naïve for SARS-CoV-2 infection. We observed no significant differences in anti-spike (S) IgG and T-cell responses according to the 25OHD status at baseline. However, significant correlations between the 25OHD concentration at baseline and (i) the anti-S response (p < 0.020) and (ii) the neutralizing antibody (NT) titre (p = 0.040) at six months after the second dose were detected. We concluded that adequate levels of vitamin D may improve the immune response to mRNA vaccines such as BNT162b2, and that further larger studies are warranted in order to confirm these preliminary observations.

Share this book

Add to My Shelf

Publisher

MDPI AG,MDPI

Subject