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Adenovirus—Extracellular Protein Interactions and Their Impact on Innate Immune Responses by Human Mononuclear Phagocytes
by
Kremer, Eric J.
, Chéneau, Coraline
in
adenovirus
/ Adenovirus Infections, Human
/ Adenovirus Infections, Human - immunology
/ Adenovirus Infections, Human - virology
/ Adenoviruses
/ Adenoviruses, Human
/ Adenoviruses, Human - immunology
/ Animals
/ Antibodies
/ Antibodies, Viral
/ Antibodies, Viral - immunology
/ antibody
/ Antigens
/ Antimicrobial agents
/ antimicrobial peptide
/ Antimicrobial peptides
/ blood
/ Blood coagulation
/ capsid
/ Cell activation
/ Cellular Microenvironment
/ Clotting
/ coagulation factor
/ complement
/ Complement activation
/ Complement System Proteins
/ Complement System Proteins - immunology
/ Dendritic Cells
/ Extracellular Space
/ Extracellular Space - metabolism
/ Gene therapy
/ HIV
/ Host-Pathogen Interactions
/ Host-Pathogen Interactions - immunology
/ Human health and pathology
/ Human immunodeficiency virus
/ Humans
/ Immune response
/ Immunity, Innate
/ Immunoglobulins
/ Immunology
/ Infections
/ Infectious diseases
/ Innate immunity
/ Leukocytes (mononuclear)
/ Leukocytes, Mononuclear - immunology
/ Leukocytes, Mononuclear - metabolism
/ Life Sciences
/ Lymphocytes
/ Lymphocytes - immunology
/ Lymphocytes - metabolism
/ Mastadenovirus
/ Microbiology and Parasitology
/ Pathogens
/ Pattern recognition receptors
/ Phagocytes
/ Phagocytes - immunology
/ Phagocytes - metabolism
/ Protein interaction
/ Proteins
/ Reptiles & amphibians
/ Review
/ secretion
/ Severe acute respiratory syndrome coronavirus 2
/ Vaccines
/ Vectors (Biology)
/ Virology
/ Viruses
2020
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Adenovirus—Extracellular Protein Interactions and Their Impact on Innate Immune Responses by Human Mononuclear Phagocytes
by
Kremer, Eric J.
, Chéneau, Coraline
in
adenovirus
/ Adenovirus Infections, Human
/ Adenovirus Infections, Human - immunology
/ Adenovirus Infections, Human - virology
/ Adenoviruses
/ Adenoviruses, Human
/ Adenoviruses, Human - immunology
/ Animals
/ Antibodies
/ Antibodies, Viral
/ Antibodies, Viral - immunology
/ antibody
/ Antigens
/ Antimicrobial agents
/ antimicrobial peptide
/ Antimicrobial peptides
/ blood
/ Blood coagulation
/ capsid
/ Cell activation
/ Cellular Microenvironment
/ Clotting
/ coagulation factor
/ complement
/ Complement activation
/ Complement System Proteins
/ Complement System Proteins - immunology
/ Dendritic Cells
/ Extracellular Space
/ Extracellular Space - metabolism
/ Gene therapy
/ HIV
/ Host-Pathogen Interactions
/ Host-Pathogen Interactions - immunology
/ Human health and pathology
/ Human immunodeficiency virus
/ Humans
/ Immune response
/ Immunity, Innate
/ Immunoglobulins
/ Immunology
/ Infections
/ Infectious diseases
/ Innate immunity
/ Leukocytes (mononuclear)
/ Leukocytes, Mononuclear - immunology
/ Leukocytes, Mononuclear - metabolism
/ Life Sciences
/ Lymphocytes
/ Lymphocytes - immunology
/ Lymphocytes - metabolism
/ Mastadenovirus
/ Microbiology and Parasitology
/ Pathogens
/ Pattern recognition receptors
/ Phagocytes
/ Phagocytes - immunology
/ Phagocytes - metabolism
/ Protein interaction
/ Proteins
/ Reptiles & amphibians
/ Review
/ secretion
/ Severe acute respiratory syndrome coronavirus 2
/ Vaccines
/ Vectors (Biology)
/ Virology
/ Viruses
2020
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Adenovirus—Extracellular Protein Interactions and Their Impact on Innate Immune Responses by Human Mononuclear Phagocytes
by
Kremer, Eric J.
, Chéneau, Coraline
in
adenovirus
/ Adenovirus Infections, Human
/ Adenovirus Infections, Human - immunology
/ Adenovirus Infections, Human - virology
/ Adenoviruses
/ Adenoviruses, Human
/ Adenoviruses, Human - immunology
/ Animals
/ Antibodies
/ Antibodies, Viral
/ Antibodies, Viral - immunology
/ antibody
/ Antigens
/ Antimicrobial agents
/ antimicrobial peptide
/ Antimicrobial peptides
/ blood
/ Blood coagulation
/ capsid
/ Cell activation
/ Cellular Microenvironment
/ Clotting
/ coagulation factor
/ complement
/ Complement activation
/ Complement System Proteins
/ Complement System Proteins - immunology
/ Dendritic Cells
/ Extracellular Space
/ Extracellular Space - metabolism
/ Gene therapy
/ HIV
/ Host-Pathogen Interactions
/ Host-Pathogen Interactions - immunology
/ Human health and pathology
/ Human immunodeficiency virus
/ Humans
/ Immune response
/ Immunity, Innate
/ Immunoglobulins
/ Immunology
/ Infections
/ Infectious diseases
/ Innate immunity
/ Leukocytes (mononuclear)
/ Leukocytes, Mononuclear - immunology
/ Leukocytes, Mononuclear - metabolism
/ Life Sciences
/ Lymphocytes
/ Lymphocytes - immunology
/ Lymphocytes - metabolism
/ Mastadenovirus
/ Microbiology and Parasitology
/ Pathogens
/ Pattern recognition receptors
/ Phagocytes
/ Phagocytes - immunology
/ Phagocytes - metabolism
/ Protein interaction
/ Proteins
/ Reptiles & amphibians
/ Review
/ secretion
/ Severe acute respiratory syndrome coronavirus 2
/ Vaccines
/ Vectors (Biology)
/ Virology
/ Viruses
2020
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Adenovirus—Extracellular Protein Interactions and Their Impact on Innate Immune Responses by Human Mononuclear Phagocytes
Journal Article
Adenovirus—Extracellular Protein Interactions and Their Impact on Innate Immune Responses by Human Mononuclear Phagocytes
2020
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Overview
The aim of this review is to highlight how, in a syngeneic system, human mononuclear phagocytes respond to environments containing human adenovirus (HAdV) and soluble extracellular proteins that influence their innate immune response. Soluble extracellular proteins, including immunoglobulins, blood clotting factors, proteins of the complement system, and/or antimicrobial peptides (AMPs) can exert direct effects by binding to a virus capsid that modifies interactions with pattern recognition receptors and downstream signaling. In addition, the presence, generation, or secretion of extracellular proteins can indirectly influence the response to HAdVs via the activation and recruitment of cells at the site of infection.
Publisher
MDPI AG,MDPI
Subject
/ Adenovirus Infections, Human
/ Adenovirus Infections, Human - immunology
/ Adenovirus Infections, Human - virology
/ Adenoviruses, Human - immunology
/ Animals
/ Antibodies, Viral - immunology
/ antibody
/ Antigens
/ blood
/ capsid
/ Clotting
/ Complement System Proteins - immunology
/ Extracellular Space - metabolism
/ HIV
/ Host-Pathogen Interactions - immunology
/ Human immunodeficiency virus
/ Humans
/ Leukocytes, Mononuclear - immunology
/ Leukocytes, Mononuclear - metabolism
/ Microbiology and Parasitology
/ Pattern recognition receptors
/ Proteins
/ Review
/ Severe acute respiratory syndrome coronavirus 2
/ Vaccines
/ Virology
/ Viruses
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