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DoCM: a database of curated mutations in cancer

by Coffman, Adam C , Wilson, Richard K , Mardis, Elaine R , Ainscough, Benjamin J , Kunisaki, Jason , Wagner, Alex H , McMichael, Joshua F , Fulton, Robert S , Griffith, Malachi , Griffith, Obi L , Choudhary, Mayank NK

in 631/114/129/2043 / 631/67/69 / 692/308/2056 / 692/308/575 / Bioinformatics / Biological Microscopy / Biological Techniques / Biology / Biomedical and Life Sciences / Biomedical Engineering/Biotechnology / Cancer / Cancer genetics / correspondence / Data analysis / Gene mutation / Genomics / Healthcare industry software / Identification and classification / Innovations / Life Sciences / Mutation / Precision medicine / Proteomics

2016

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DoCM: a database of curated mutations in cancer

2016

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2016

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Journal Article

DoCM: a database of curated mutations in cancer

Coffman, Adam C,

Wilson, Richard K,

Mardis, Elaine R,

Ainscough, Benjamin J,

Kunisaki, Jason,

Wagner, Alex H,

McMichael, Joshua F,

Fulton, Robert S,

Griffith, Malachi,

Griffith, Obi L,

Choudhary, Mayank NK

2016

Overview

Large-scale cancer genomics discovery projects such as The Cancer Genome Atlas (TCGA) and the International Cancer Genome Consortium (ICGC) have systematically characterized the molecular lesions in human cancer genomes, thereby laying the foundation for precision cancer medicine. However, a curated set of somatic variants with established relevance to cancer biology is essential for clinical annotation and for use in computational data analysis. We have created a database of curated mutations in cancer.

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Publisher

Nature Publishing Group US,Nature Publishing Group

Subject

/ Biological Microscopy

/ Biological Techniques