Journal Article

Remediating reduced memory specificity in bipolar disorder: A case study using a Computerized Memory Specificity Training

Martens, Kris, Takano, Keisuke, Raes, Filip, Wyckaert, Sabine, Holmes, Emily A., Barry, Tom J.

2019

Overview

Objectives Reduced autobiographical memory specificity (rAMS) is a vulnerability factor found across unipolar depression (UD), posttraumatic stress disorder (PTSD), eating disorder, schizophrenia, and bipolar disorder (BD). A group delivered psychological therapy training called Memory Specificity Training (MeST) remediates rAMS in UD and PTSD, with additional downstream effects on related psychological processes and symptoms. Its impact in BD is unknown. In this case study, we examined the impact of a computerized version of MeST (c‐MeST) on improving AMS and related symptoms and processes in participant with rapid cycling type I BD. Method An experimental case study with an ABA design was used. During baseline (14 days, Phase A), the training phase (nine sessions across 17 days, Phase B), and a 1‐month follow‐up (Phase A), memory specificity, depressive symptoms, and related processes and symptoms were repeatedly measured. Results Memory specificity increased significantly after the participant completed c‐MeST. Session‐to‐session scores indicated that AMS improved most from the in‐person baseline assessment to the first online session. All other measures of processes and symptoms deteriorated during the training phase but regressed to baseline during follow‐up. Conclusion Memory specificity was improved as indicated by increased AMS from pre‐intervention measurement to 1‐month follow‐up. Other improvements in symptoms were not observed. Rather, some related maladaptive psychological processes and symptoms worsened during the training phase and regressed to baseline during follow‐up. In an experimental single case study autobiographical memory specificity was successfully remediated, from pre‐intervention measurement to 1‐month follow‐up, by using an online memory specificity training, in one person with rapid cycling Bipolar Disorder type I. Other improvements in symptoms were not observed. Rather, some related maladaptive psychological processes and symptoms worsened during the training phase and regressed to baseline during follow up.

• Publisher: John Wiley & Sons, Inc,John Wiley and Sons Inc,Wiley
• Subject: Adult / autobiographical memory / Bipolar disorder / Bipolar Disorder - physiopathology / Bipolar Disorder - psychology / Computer-Aided Design / Emotions / Feedback / Female / Humans / Intervention / Learning / Male / Memory / Memory Disorders - diagnosis / Memory Disorders - psychology / Memory Specificity Training / Memory, Episodic / Neurosciences / Original Research / Outcome Assessment, Health Care / Post traumatic stress disorder / Problem solving / Psychology / Psykologi / reduced autobiographical memory specificity / Schizophrenia