Asset Details

MbrlCatalogueTitleDetail

Do you wish to reserve the book?

Comprehensive assessment of physiological responses in women during the ESA dry immersion VIVALDI microgravity simulation

by Chopard, Angèle , Cardiovasculaire, métabolisme, diabétologie et nutrition (CarMeN) ; Université Claude Bernard Lyon 1 (UCBL) ; Université de Lyon-Université de Lyon-Hospices Civils de Lyon (HCL)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Institut National de Recherche pour l’Agriculture, l’Alimentation et l’Environnement (INRAE) , Vico, Laurence , Centre for Human Nutrition ; University of Colorado Anschutz Medical Campus [Aurora] , Telespazio ; Services par satellites , Université de Montpellier (UM) , Kermorgant, Marc , Rosnet, Elisabeth , Mobilités : Vieillissement, Pathologie, Santé (COMETE) ; Université de Caen Normandie (UNICAEN) ; Normandie Université (NU)-Normandie Université (NU)-Institut National de la Santé et de la Recherche Médicale (INSERM) , van Ombergen, Angelique , Choukér, Alexander , Dynamique du Muscle et Métabolisme (DMEM) ; Institut National de Recherche pour l’Agriculture, l’Alimentation et l’Environnement (INRAE)-Université de Montpellier (UM) , Institut Pluridisciplinaire

in 631/443/319 / 631/443/592 / 631/443/63 / Aerobic capacity / Astronauts / Bone growth / Bone remodeling / Bone resorption / Deconditioning / Earth gravitation / Glucose tolerance / Humanities and Social Sciences / Immersion / Life Sciences / Lipids / Metabolic disorders / Metabolic syndrome / Microgravity / multidisciplinary / Orthostatic tolerance / Osteogenesis / Physiological responses / Physiology / Science / Science (multidisciplinary) / Sensorimotor system / Sex / Simulation / Submerging / Unloading / Women

2023

Yes Please

Hey, we have placed the reservation for you!

By the way, why not check out events that you can attend while you pick your title.

Oops! Something went wrong.

Looks like we were not able to place the reservation. Kindly try again later.

Are you sure you want to remove the book from the shelf?

Comprehensive assessment of physiological responses in women during the ESA dry immersion VIVALDI microgravity simulation

2023

Confirm

Do you wish to request the book?

Comprehensive assessment of physiological responses in women during the ESA dry immersion VIVALDI microgravity simulation

2023

Please be aware that the book you have requested cannot be checked out. If you would like to checkout this book, you can reserve another copy

How would you like to get it?

Submit

We have requested the book for you!

Your request is successful and it will be processed during the Library working hours. Please check the status of your request in My Requests.

Oops! Something went wrong.

Looks like we were not able to place your request. Kindly try again later.

Journal Article

Comprehensive assessment of physiological responses in women during the ESA dry immersion VIVALDI microgravity simulation

Chopard, Angèle,

Cardiovasculaire, métabolisme, diabétologie et nutrition (CarMeN) ; Université Claude Bernard Lyon 1 (UCBL) ; Université de Lyon-Université de Lyon-Hospices Civils de Lyon (HCL)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Institut National de Recherche pour l’Agriculture, l’Alimentation et l’Environnement (INRAE),

Vico, Laurence,

Centre for Human Nutrition ; University of Colorado Anschutz Medical Campus [Aurora],

Telespazio ; Services par satellites,

Université de Montpellier (UM),

Kermorgant, Marc,

Rosnet, Elisabeth,

Mobilités : Vieillissement, Pathologie, Santé (COMETE) ; Université de Caen Normandie (UNICAEN) ; Normandie Université (NU)-Normandie Université (NU)-Institut National de la Santé et de la Recherche Médicale (INSERM),

van Ombergen, Angelique,

Choukér, Alexander,

Dynamique du Muscle et Métabolisme (DMEM) ; Institut National de Recherche pour l’Agriculture, l’Alimentation et l’Environnement (INRAE)-Université de Montpellier (UM),

Institut Pluridisciplinaire

2023

Overview

Astronauts in microgravity experience multi-system deconditioning, impacting their inflight efficiency and inducing dysfunctions upon return to Earth gravity. To fill the sex gap of knowledge in the health impact of spaceflights, we simulate microgravity with a 5-day dry immersion in 18 healthy women (Clin-icalTrials.gov Identifier: NCT05043974). Here we show that dry immersion rapidly induces a sedentarily-like metabolism shift mimicking the beginning of a metabolic syndrome with a drop in glucose tolerance, an increase in the atherogenic index of plasma, and an impaired lipid profile. Bone remodeling markers suggest a decreased bone formation coupled with an increased bone resorption. Fluid shifts and muscular unloading participate to a marked cardiovascular and sensorimotor deconditioning with decreased orthostatic tolerance, aerobic capacity, and postural balance. Collected datasets provide a comprehensive multi-systemic assessment of dry immersion effects in women and pave the way for future sex-based evaluations of countermeasures.

Share this book

Add to My Shelf

Publisher

Nature Publishing Group,CCSD,Nature Publishing Group UK,Nature Portfolio

Subject