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Current status and future perspectives of liquid biopsy in non-small cell lung cancer
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Current status and future perspectives of liquid biopsy in non-small cell lung cancer
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Journal Article
Current status and future perspectives of liquid biopsy in non-small cell lung cancer
2020
Overview
With advances in target therapy, molecular analysis of tumors is routinely required for treatment decisions in patients with advanced non-small cell lung cancer (NSCLC). Liquid biopsy refers to the sampling and analysis of circulating cell-free tumor DNA (ctDNA) in various body fluids, primarily blood. Because the technique is minimally invasive, liquid biopsies are the future in cancer management. Epidermal growth factor receptor (EGFR) ctDNA tests have been performed in routine clinical practice in advanced NSCLC patients to guide tyrosine kinase inhibitor treatment. In the near future, liquid biopsy will be a crucial prognostic, predictive, and diagnostic method in NSCLC. Here we present the current status and future perspectives of liquid biopsy in NSCLC.
Publisher
Korean Society of Pathologists, Korean Society for Cytopathology,The Korean Society of Pathologists and the Korean Society for Cytopathology,Korean Society of Pathologists & the Korean Society for Cytopathology,대한병리학회
Subject
