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Modular barcode beads for microfluidic single cell genomics
by
Abate, Adam R.
, Delley, Cyrille L.
in
631/1647/2163
/ 631/1647/2217
/ 631/1647/2217/2018
/ 631/208/69
/ 631/337/2019
/ Biomarkers, Tumor
/ DNA Barcoding, Taxonomic
/ Gene Expression Profiling
/ Gene Expression Regulation, Neoplastic
/ Genomics
/ Genomics - methods
/ Humanities and Social Sciences
/ Humans
/ Microfluidics
/ Microfluidics - methods
/ multidisciplinary
/ Neoplasms - etiology
/ Nucleic acids
/ Science
/ Science (multidisciplinary)
/ Single-Cell Analysis - methods
/ Transcriptome
2021
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Modular barcode beads for microfluidic single cell genomics
by
Abate, Adam R.
, Delley, Cyrille L.
in
631/1647/2163
/ 631/1647/2217
/ 631/1647/2217/2018
/ 631/208/69
/ 631/337/2019
/ Biomarkers, Tumor
/ DNA Barcoding, Taxonomic
/ Gene Expression Profiling
/ Gene Expression Regulation, Neoplastic
/ Genomics
/ Genomics - methods
/ Humanities and Social Sciences
/ Humans
/ Microfluidics
/ Microfluidics - methods
/ multidisciplinary
/ Neoplasms - etiology
/ Nucleic acids
/ Science
/ Science (multidisciplinary)
/ Single-Cell Analysis - methods
/ Transcriptome
2021
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Modular barcode beads for microfluidic single cell genomics
by
Abate, Adam R.
, Delley, Cyrille L.
in
631/1647/2163
/ 631/1647/2217
/ 631/1647/2217/2018
/ 631/208/69
/ 631/337/2019
/ Biomarkers, Tumor
/ DNA Barcoding, Taxonomic
/ Gene Expression Profiling
/ Gene Expression Regulation, Neoplastic
/ Genomics
/ Genomics - methods
/ Humanities and Social Sciences
/ Humans
/ Microfluidics
/ Microfluidics - methods
/ multidisciplinary
/ Neoplasms - etiology
/ Nucleic acids
/ Science
/ Science (multidisciplinary)
/ Single-Cell Analysis - methods
/ Transcriptome
2021
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Modular barcode beads for microfluidic single cell genomics
Journal Article
Modular barcode beads for microfluidic single cell genomics
2021
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Overview
Barcode beads allow efficient nucleic acid tagging in single cell genomics. Current barcode designs, however, are fabricated with a particular application in mind. Repurposing to novel targets, or altering to add additional targets as information is obtained is possible but the result is suboptimal. Here, we describe a modular framework that simplifies generation of multifunctional beads and allows their easy extension to new targets.
Publisher
Nature Publishing Group UK,Nature Publishing Group,Nature Portfolio
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