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Oral field cancerization and its clinical implications in the management in potentially malignant disorders

by Arul Prakash, AA , Jaish Lal, MS , Goma Kumar, KU , Sathiasekar, AnishaCynthia , Mathew, DeepuGeorge

in Care and treatment / Clinical outcomes / Development and progression / Field cancerization / Genetic aspects / genetically altered / Health aspects / Hospitals / Innovations / Management / Medical prognosis / Metastasis / Mouth cancer / Mutation / Oncogenes / Oral cancer / patches / Pathology / potentially malignant disorders / Public health administration / Review / Tumors

2017

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Oral field cancerization and its clinical implications in the management in potentially malignant disorders

by Arul Prakash, AA , Jaish Lal, MS , Goma Kumar, KU , Sathiasekar, AnishaCynthia , Mathew, DeepuGeorge

2017

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Oral field cancerization and its clinical implications in the management in potentially malignant disorders

by Arul Prakash, AA , Jaish Lal, MS , Goma Kumar, KU , Sathiasekar, AnishaCynthia , Mathew, DeepuGeorge

2017

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Journal Article

Oral field cancerization and its clinical implications in the management in potentially malignant disorders

Arul Prakash, AA,

Jaish Lal, MS,

Goma Kumar, KU,

Sathiasekar, AnishaCynthia,

Mathew, DeepuGeorge

2017

Overview

Oral cancer is one of the common malignancies reported in India. Most of these cancers are preceded by potentially malignant disorders. Despite improvements in the management strategies of these cancers the posttreatment prognosis has remained poor. The 5-year survival rates of oral cancers in most countries are still below 50%. The poor outcomes in oral cancer prevention and treatment can be due to nature of the spread of genetically altered cells as fields within the epithelial compartment. The conventional management protocols need to be modified taking into consideration the field spread of genetically altered cells.

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Publisher

Medknow Publications and Media Pvt. Ltd,Medknow Publications & Media Pvt. Ltd,Medknow Publications & Media Pvt Ltd,Wolters Kluwer Medknow Publications

Subject

Care and treatment

/ Clinical outcomes

/ Development and progression

/ Field cancerization

/ Genetic aspects

/ genetically altered