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Analysis of the cost-effectiveness of surfactant treatment (Curosurf®) in respiratory distress syndrome therapy in preterm infants: early treatment compared to late treatment
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Analysis of the cost-effectiveness of surfactant treatment (Curosurf®) in respiratory distress syndrome therapy in preterm infants: early treatment compared to late treatment
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Analysis of the cost-effectiveness of surfactant treatment (Curosurf®) in respiratory distress syndrome therapy in preterm infants: early treatment compared to late treatment
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Journal Article
Analysis of the cost-effectiveness of surfactant treatment (Curosurf®) in respiratory distress syndrome therapy in preterm infants: early treatment compared to late treatment
2014
Overview
Background
The best criteria for surfactant treatment in the perinatal period are unknown and this makes it of interest to consider the possible economic implications of lessening the use of more restrictive criteria.
Objective
The objective of this study is the evaluation of the costs of respiratory care for preterm infants with Respiratory Distress Syndrome (RDS) treated with \"early rescue\" surfactant compared to a \"late rescue\" strategy.
Methods
The study was carried out applying the costs of materials used, of staff and pharmacological therapy calculated in the Neonatal Intensive Care Unit (NICU) of an Italian hospital to the Verder
et al
. study (Pediatrics 1999) clinical data.
Results
The cost for patients treated with
early
strategy was slightly lower than for patients treated with
late
strategy (Euro 4,901.70 vs. Euro 4,960.07). The cost of treatment with surfactant was greater in the
early group
(Euro 458.49 vs. Euro 311.74), but this was compensated by the greater cost of treatment with Mechanical Ventilation (MV) in the
late
group (respectively Euro 108.85 vs. Euro 259.25).
Conclusions
The cost-effectiveness analysis performed in this study shows how
early
treatment with surfactant in preterm infants with RDS, as well as being clinically more effective, is associated with a slightly lower cost.
Publisher
BioMed Central,Springer Nature B.V
Subject
Biological Products - administration & dosage
/ Biological Products - therapeutic use
/ Female
/ Hospital Costs - statistics & numerical data
/ Humans
/ Infant, Premature, Diseases - economics
/ Infant, Premature, Diseases - therapy
/ Male
/ Medicine
/ Neonatology and Fetal Medicine
/ Phospholipids - administration & dosage
/ Phospholipids - therapeutic use
/ Pulmonary Surfactants - administration & dosage
/ Pulmonary Surfactants - therapeutic use
/ Respiration, Artificial - economics
/ Respiration, Artificial - methods
/ Respiratory Care Units - economics
/ Respiratory Distress Syndrome, Newborn - economics
