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Surgical myectomy might inhibit ascending aortic dilation in obstructive hypertrophic cardiomyopathy: a serial cardiac magnetic resonance study
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Surgical myectomy might inhibit ascending aortic dilation in obstructive hypertrophic cardiomyopathy: a serial cardiac magnetic resonance study
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Journal Article
Surgical myectomy might inhibit ascending aortic dilation in obstructive hypertrophic cardiomyopathy: a serial cardiac magnetic resonance study
2025
Overview
Background
The impact of septal myectomy on the progression of ascending aortic (AAo) dilation in patients with obstructive hypertrophic cardiomyopathy (HOCM) remains uncertain. This study aimed to investigate the relationship between septal myectomy and AAo dilation in HOCM patients.
Methods
A total of 69 patients with HOCM were enrolled. All the participants underwent sequential cardiac magnetic resonance scans at a mean interval of 5.13 ± 2.04 years, with each scan being more than 3 years apart.
Results
At baseline, 17 patients with HOCM (25%) exhibited AAo dilation (Indexed AAo dimension > 19 mm/m²). Age (OR 1.10, 95%CI: 1.01–1.019,
P
= 0.026) and female (OR 4.80, 95%CI: 1.05–21.93,
P
= 0.043) were independently associated with AAo dilation. In patients who underwent myectomy, the AAo dimension at follow-up was similar to that at baseline (32.47 ± 4.70 mm vs. 32.81 ± 5.06 mm,
P
= 0.197). Furthermore, the rate of AAo dilation was lower in patients with myectomy compared to those without myectomy (-0.06 ± 0.38 mm/year vs. 0.18 ± 0.43 mm/year,
P
= 0.016). Additionally, moderate or severe mitral regurgitation was significantly associated with AAo dilation rate (B = 0.273,
P
= 0.032).
Conclusions
Myectomy in patients with HOCM was associated with the absence of progression of AAo dilatation.
Publisher
BioMed Central,BioMed Central Ltd,Springer Nature B.V,BMC
Subject
/ Age
/ Aged
/ Aorta
/ Cardiac Surgical Procedures - methods
/ Cardiomyopathy, Hypertrophic
/ Cardiomyopathy, Hypertrophic - complications
/ Cardiomyopathy, Hypertrophic - surgery
/ Dilatation, Pathologic - prevention & control
/ Female
/ Females
/ Heart
/ Humans
/ Magnetic Resonance Imaging, Cine - methods
/ Male
/ Medicine
/ Patients
/ Scanners
