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Incidence and risk factors for early transient intraocular pressure elevation after penetrating canaloplasty in patients with glaucoma
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Incidence and risk factors for early transient intraocular pressure elevation after penetrating canaloplasty in patients with glaucoma
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Journal Article
Incidence and risk factors for early transient intraocular pressure elevation after penetrating canaloplasty in patients with glaucoma
2025
Overview
Background
This study aimed to evaluate the incidence and risk factors for early transient intraocular pressure (IOP) elevation after penetrating canaloplasty (PCP) in patients with primary open-angle glaucoma (POAG), primary angle-closure glaucoma (PACG) and secondary glaucoma (SG).
Methods
This retrospective study included 198 eyes of 198 patients with glaucoma. Participants were classified as normal IOP, early transient high IOP (E-HIOP [Tst]), early persistent IOP elevation, late transient high IOP, and late persistent IOP elevation, based on the period and persistence of postoperative IOP elevation.
Results
E-HIOP (Tst) developed in 34.8%, 33.3%, and 40.9% of eyes with POAG, PACG, and SG, respectively. In comparison with normal IOP group, we observed the following variations in E-HIOP (Tst) cohorts: 8 − 10 years younger in patients with POAG and PACG; higher prevalence of hyphema (45.5% vs. 20.5%) in POAG; higher baseline IOP in PACG and SG (7 − 8 mmHg); higher preoperative IOP maximum (IOP
pre−max
) in SG (all
p
< 0.05). Higher IOP
pre−max
was a risk factor for E-HIOP (Tst) in PACG and SG (
p
< 0.05).
Conclusions
Nearly 30 − 40% of eyes developed E-HIOP (Tst) after PCP. E-HIOP (Tst) tended to develop in younger participants and those with higher preoperative IOP. A higher IOP
pre−max
was a risk factor for E-HIOP (Tst) in PACG and SG.
Publisher
BioMed Central,BioMed Central Ltd,Springer Nature B.V,BMC
Subject
/ Early postoperative IOP elevation
/ Eye
/ Female
/ Filtering Surgery - adverse effects
/ Glaucoma
/ Glaucoma, Angle-Closure - physiopathology
/ Glaucoma, Angle-Closure - surgery
/ Glaucoma, Open-Angle - physiopathology
/ Glaucoma, Open-Angle - surgery
/ Humans
/ Male
/ Medicine
/ Minimally Invasive Surgical Procedures - adverse effects
/ Minimally Invasive Surgical Procedures - methods
/ Ocular Hypertension - etiology
/ Postoperative Complications - physiopathology
/ Steroids
/ Surgery
