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Improving the accuracy of medical diagnosis with causal machine learning
by
Lee, Ciarán M.
, Johri, Saurabh
, Richens, Jonathan G.
in
631/114/2413
/ 639/705/531
/ 692/700/139
/ Accuracy
/ Algorithms
/ Bayes Theorem
/ Causation
/ Data Accuracy
/ Data Collection
/ Decision Making
/ Diagnosis
/ Diagnosis, Computer-Assisted
/ Diagnostic systems
/ Disease
/ Humanities and Social Sciences
/ Humans
/ Inference
/ Learning algorithms
/ Machine Learning
/ Medical diagnosis
/ Models, Statistical
/ multidisciplinary
/ Patients
/ Physicians
/ Science
/ Science (multidisciplinary)
/ Signs and symptoms
2020
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Improving the accuracy of medical diagnosis with causal machine learning
by
Lee, Ciarán M.
, Johri, Saurabh
, Richens, Jonathan G.
in
631/114/2413
/ 639/705/531
/ 692/700/139
/ Accuracy
/ Algorithms
/ Bayes Theorem
/ Causation
/ Data Accuracy
/ Data Collection
/ Decision Making
/ Diagnosis
/ Diagnosis, Computer-Assisted
/ Diagnostic systems
/ Disease
/ Humanities and Social Sciences
/ Humans
/ Inference
/ Learning algorithms
/ Machine Learning
/ Medical diagnosis
/ Models, Statistical
/ multidisciplinary
/ Patients
/ Physicians
/ Science
/ Science (multidisciplinary)
/ Signs and symptoms
2020
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Do you wish to request the book?
Improving the accuracy of medical diagnosis with causal machine learning
by
Lee, Ciarán M.
, Johri, Saurabh
, Richens, Jonathan G.
in
631/114/2413
/ 639/705/531
/ 692/700/139
/ Accuracy
/ Algorithms
/ Bayes Theorem
/ Causation
/ Data Accuracy
/ Data Collection
/ Decision Making
/ Diagnosis
/ Diagnosis, Computer-Assisted
/ Diagnostic systems
/ Disease
/ Humanities and Social Sciences
/ Humans
/ Inference
/ Learning algorithms
/ Machine Learning
/ Medical diagnosis
/ Models, Statistical
/ multidisciplinary
/ Patients
/ Physicians
/ Science
/ Science (multidisciplinary)
/ Signs and symptoms
2020
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Improving the accuracy of medical diagnosis with causal machine learning
Journal Article
Improving the accuracy of medical diagnosis with causal machine learning
2020
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Overview
Machine learning promises to revolutionize clinical decision making and diagnosis. In medical diagnosis a doctor aims to explain a patient’s symptoms by determining the diseases causing them. However, existing machine learning approaches to diagnosis are purely associative, identifying diseases that are strongly correlated with a patients symptoms. We show that this inability to disentangle correlation from causation can result in sub-optimal or dangerous diagnoses. To overcome this, we reformulate diagnosis as a counterfactual inference task and derive counterfactual diagnostic algorithms. We compare our counterfactual algorithms to the standard associative algorithm and 44 doctors using a test set of clinical vignettes. While the associative algorithm achieves an accuracy placing in the top 48% of doctors in our cohort, our counterfactual algorithm places in the top 25% of doctors, achieving expert clinical accuracy. Our results show that causal reasoning is a vital missing ingredient for applying machine learning to medical diagnosis.
In medical diagnosis a doctor aims to explain a patient’s symptoms by determining the diseases causing them, while existing diagnostic algorithms are purely associative. Here, the authors reformulate diagnosis as a counterfactual inference task and derive new counterfactual diagnostic algorithms.
Publisher
Nature Publishing Group UK,Nature Publishing Group,Nature Portfolio
Subject
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