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Probiotic bacteria reduced duration and severity but not the incidence of common cold episodes in a double blind, randomized, controlled trial
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Probiotic bacteria reduced duration and severity but not the incidence of common cold episodes in a double blind, randomized, controlled trial
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Journal Article
Probiotic bacteria reduced duration and severity but not the incidence of common cold episodes in a double blind, randomized, controlled trial
2006
Overview
To investigate the effect of long-term consumption of probiotic bacteria on viral respiratory tract infections (common cold, influenza), a randomized, double blind, controlled intervention study was performed during two winter/spring periods (3 and 5 month). Four hundred and seventy-nine healthy adults were supplemented daily with vitamins plus minerals with or without probiotic lactobacilli and bifidobacteria. The intake of the probiotic had no effect on the incidence of common cold infections (verum
=
158, control
=
153 episodes, influenza was not observed), but significantly shortened duration of episodes by almost 2 days (7.0
±
0.5 versus 8.9
±
1.0 days,
p
=
0.045), reduced the severity of symptoms and led to larger increases in cytotoxic T plus T suppressor cell counts and in T helper cell counts.
Publisher
Elsevier Ltd,Elsevier,Elsevier Limited
Subject
/ Adult
/ Aged
/ Bacteria
/ Biological and medical sciences
/ Common Cold - physiopathology
/ Common Cold - prevention & control
/ DNA
/ Female
/ Fundamental and applied biological sciences. Psychology
/ Humans
/ Immunity, Cellular - drug effects
/ Immunity, Cellular - physiology
/ Male
/ Probiotics - therapeutic use
/ Respiratory tract infections
/ Respiratory Tract Infections - classification
/ Respiratory Tract Infections - epidemiology
/ Respiratory Tract Infections - prevention & control
/ Vaccines, antisera, therapeutical immunoglobulins and monoclonal antibodies (general aspects)
/ Viral diseases of the respiratory system and ent viral diseases
/ Vitamins
