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On a phenomenological model for active smooth muscle contraction
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On a phenomenological model for active smooth muscle contraction
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Journal Article
On a phenomenological model for active smooth muscle contraction
2011
Overview
This paper presents a three-dimensional phenomenological model for the description of smooth muscle activation. A strain energy function is proposed as sum of the strain energy stored in the passive tissue, consisting of elastin and collagen, and an active calcium-driven energy related to the chemical contraction of the smooth muscle cells. Further, the proposed model includes the dispersions of the orientations of smooth muscle cells and collagen. These dispersions, measured in experiments, can be directly inserted into the model. The approach is implemented into the framework of the finite element method. Consequently, beside a validation with experiments the modelling concept is used for a three-dimensional numerical study.
Publisher
Elsevier Ltd,Elsevier,Elsevier Limited
Subject
/ Biological and medical sciences
/ Calcium
/ Collagen
/ Fundamental and applied biological sciences. Psychology
/ Muscle Contraction - physiology
/ Muscles
/ Myocytes, Smooth Muscle - metabolism
/ Myocytes, Smooth Muscle - physiology
/ Physical Medicine and Rehabilitation
/ Strain
