Asset Details

MbrlCatalogueTitleDetail

Do you wish to reserve the book?

SRC kinase-mediated signaling pathways and targeted therapies in breast cancer

by Zou, Hailin , Ye, Liping , Wang, Bo , Tong, Tongyu , Pan, Yihang , Guo, Yibo , Deng, Liang , Li, Peng , Luo, Juan , Zhu, Chengming

in Biomedical and Life Sciences / Biomedicine / Breast cancer / Breast Neoplasms - drug therapy / Breast Neoplasms - genetics / Cancer / Cancer Research / Care and treatment / Cells / Cellular signal transduction / Development and progression / Drug resistance / Female / Health aspects / Humans / Metastasis / Oncology / PDGFB in breast cancer initiation / Pertuzumab / Phosphorylation / progression / Review / Signal Transduction / Signaling transduction / SRC kinase / src-Family Kinases - genetics / src-Family Kinases - metabolism / Surgical Oncology / Targeted therapy / Tyrosine / Tyrosine phosphorylation

2022

Yes Please

Hey, we have placed the reservation for you!

By the way, why not check out events that you can attend while you pick your title.

Oops! Something went wrong.

Looks like we were not able to place the reservation. Kindly try again later.

Are you sure you want to remove the book from the shelf?

SRC kinase-mediated signaling pathways and targeted therapies in breast cancer

by Zou, Hailin , Ye, Liping , Wang, Bo , Tong, Tongyu , Pan, Yihang , Guo, Yibo , Deng, Liang , Li, Peng , Luo, Juan , Zhu, Chengming

2022

Confirm

Do you wish to request the book?

SRC kinase-mediated signaling pathways and targeted therapies in breast cancer

by Zou, Hailin , Ye, Liping , Wang, Bo , Tong, Tongyu , Pan, Yihang , Guo, Yibo , Deng, Liang , Li, Peng , Luo, Juan , Zhu, Chengming

2022

Please be aware that the book you have requested cannot be checked out. If you would like to checkout this book, you can reserve another copy

How would you like to get it?

Submit

We have requested the book for you!

Your request is successful and it will be processed during the Library working hours. Please check the status of your request in My Requests.

Oops! Something went wrong.

Looks like we were not able to place your request. Kindly try again later.

Journal Article

SRC kinase-mediated signaling pathways and targeted therapies in breast cancer

Zou, Hailin,

Ye, Liping,

Wang, Bo,

Tong, Tongyu,

Pan, Yihang,

Guo, Yibo,

Deng, Liang,

Li, Peng,

Luo, Juan,

Zhu, Chengming

2022

Overview

Breast cancer (BC) has been ranked the most common malignant tumor throughout the world and is also a leading cause of cancer-related deaths among women. SRC family kinases (SFKs) belong to the non-receptor tyrosine kinase (nRTK) family, which has eleven members sharing similar structure and function. Among them, SRC is the first identified proto-oncogene in mammalian cells. Oncogenic overexpression or activation of SRC has been revealed to play essential roles in multiple events of BC progression, including tumor initiation, growth, metastasis, drug resistance and stemness regulations. In this review, we will first give an overview of SRC kinase and SRC-relevant functions in various subtypes of BC and then systematically summarize SRC-mediated signaling transductions, with particular emphasis on SRC-mediated substrate phosphorylation in BC. Furthermore, we will discuss the progress of SRC-based targeted therapies in BC and the potential future direction.

Share this book

Add to My Shelf

Publisher

BioMed Central,BioMed Central Ltd,BMC

Subject

Biomedical and Life Sciences

/ Biomedicine

/ Breast cancer

/ Breast Neoplasms - drug therapy

/ Breast Neoplasms - genetics

/ Cancer

/ Cancer Research