Journal Article

The Burden of Respiratory Syncytial Virus Infection in Young Children

Erdman, Dean, Poehling, Katherine A, Staat, Mary A, Szilagyi, Peter, Iwane, Marika K, Grijalva, Carlos G, Griffin, Marie R, Zhu, Yuwei, Blumkin, Aaron K, Hall, Caroline Breese, Weinberg, Geoffrey A, Edwards, Kathryn M, Auinger, Peggy

2009

Overview

In this prospective, population-based survey of children under the age of 5 years, respiratory syncytial virus (RSV) was shown to be associated with 20% of hospitalizations, 18% of emergency department visits, and 15% of office visits for acute respiratory infections during the winter. Only 3% of the outpatient RSV infections were specifically diagnosed. In children under the age of 5 years, respiratory syncytial virus was shown to be associated with 20% of hospitalizations, 18% of emergency department visits, and 15% of office visits for acute respiratory infections during the winter. The primary role of respiratory syncytial virus (RSV) in causing lower respiratory disease among infants has made its control a worldwide priority. 1 , 2 However, in the United States, the total burden of RSV infection during the first 5 years of life remains poorly defined, particularly in the outpatient setting. Previous studies have been limited because they were retrospective, of short duration, lacked laboratory confirmation of RSV infection, or focused only on hospitalizations or bronchiolitis. 3 – 8 The Centers for Disease Control and Prevention (CDC) initiated the New Vaccine Surveillance Network (NVSN), a prospective, population-based inpatient and outpatient surveillance for acute respiratory . . .

• Publisher: Massachusetts Medical Society
• Subject: Age / Ambulatory Care - utilization / Biological and medical sciences / Chi-Square Distribution / Child, Preschool / Departments / Emergency Service, Hospital - utilization / Female / General aspects / Hospitalization / Hospitalization - statistics & numerical data / Human viral diseases / Humans / Infant / Infant, Newborn / Infectious diseases / Influenza / Logistic Models / Male / Medical sciences / Population Surveillance / Prospective Studies / Respiratory diseases / Respiratory Syncytial Virus Infections - epidemiology / Respiratory Syncytial Viruses - isolation & purification / Respiratory Tract Infections - epidemiology / Respiratory Tract Infections - virology / Risk Factors / United States - epidemiology / Viral diseases / Viral diseases of the respiratory system and ent viral diseases