Asset Details

MbrlCatalogueTitleDetail

Do you wish to reserve the book?

Fruquintinib-induced renal-limited thrombotic microangiopathy: a case report

by Wang, Ying , Han, Yuze , Fan, Ruichen , Chen, Weidong , Zhao, Ruiping , Pan, Yan

in Aged / B cells / Biopsy / Blood pressure / Cancer therapies / Case Report / Case studies / Colon cancer / Colonic Neoplasms - drug therapy / Colorectal cancer / Development and progression / Diagnosis / Drug therapy / Endothelium / Fuquinitinib / Humans / Internal Medicine / Kidney diseases / Kidneys / Kinases / Male / Medical research / Medicine / Medicine & Public Health / Medicine, Experimental / Metastases / Metastasis / Nephrology / Pathology / Proteins / Proteinuria / Quinazolines - adverse effects / Quinazolines - therapeutic use / Renal restriction / Risk factors / Thrombotic Microangiopathies - chemically induced / Thrombotic microangiopathy / Vascular endothelial growth factor / Vascular endothelial growth factor receptors

2024

Yes Please

Hey, we have placed the reservation for you!

By the way, why not check out events that you can attend while you pick your title.

Oops! Something went wrong.

Looks like we were not able to place the reservation. Kindly try again later.

Are you sure you want to remove the book from the shelf?

Fruquintinib-induced renal-limited thrombotic microangiopathy: a case report

by Wang, Ying , Han, Yuze , Fan, Ruichen , Chen, Weidong , Zhao, Ruiping , Pan, Yan

2024

Confirm

Do you wish to request the book?

Fruquintinib-induced renal-limited thrombotic microangiopathy: a case report

by Wang, Ying , Han, Yuze , Fan, Ruichen , Chen, Weidong , Zhao, Ruiping , Pan, Yan

2024

Please be aware that the book you have requested cannot be checked out. If you would like to checkout this book, you can reserve another copy

How would you like to get it?

Submit

We have requested the book for you!

Your request is successful and it will be processed during the Library working hours. Please check the status of your request in My Requests.

Oops! Something went wrong.

Looks like we were not able to place your request. Kindly try again later.

Journal Article

Fruquintinib-induced renal-limited thrombotic microangiopathy: a case report

Wang, Ying,

Han, Yuze,

Fan, Ruichen,

Chen, Weidong,

Zhao, Ruiping,

Pan, Yan

2024

Overview

Background Fruquintinib is a highly selective inhibitor of vascular endothelial growth factor receptor (VEGFR). Currently, there are no reported cases of fruquintinib causing kidney-restrictive thrombotic microangiopathy (TMA) in the available Chinese and foreign literature. Case presentation In this case report, we presented a 73-year-old patient receiving fruquintinib for metastatic colon cancer, manifesting abundant proteinuria, in which kidney-restrictive TMA was also diagnosed through renal biopsy. As far as we were concerned, this was the frst reported in terms of fruquintinib-induced kidney-restrictive TMA confrmed by renal biopsy. Conclusion This case indicates that fruquintinib may result in kidney-restrictive TMA, which is a rare but life-threatening complication of cancer treatment drug. Therefore, regular monitoring of proteinuria and blood pressure is imperative for all patients undergoing anti-VEGF drug therapy. And renal biopsy should be promptly conducted to facilitate early detection of thrombotic microangiopathy.

Share this book

Add to My Shelf

Publisher

BioMed Central,BioMed Central Ltd,Springer Nature B.V,BMC

Subject

Aged

/ B cells

/ Biopsy