Journal Article

Stereotactic Radiosurgery for Intracranial Noncavernous Sinus Benign Meningioma: International Stereotactic Radiosurgery Society Systematic Review, Meta-Analysis and Practice Guideline

Sheehan, Jason, Yomo, Shoji, De Salles, Antonio A F, Sahgal, Arjun, Pollock, Bruce E, Marchetti, Marcello, Fariselli, Laura, Ma, Lijun, Levivier, Marc, Regis, Jean, Paddick, Ian, Suh, John H

2020

Overview

Abstract BACKGROUND Stereotactic radiosurgery (SRS) for benign intracranial meningiomas is an established treatment. OBJECTIVE To summarize the literature and provide evidence-based practice guidelines on behalf of the International Stereotactic Radiosurgery Society (ISRS). METHODS Articles in English specific to SRS for benign intracranial meningioma, published from January 1964 to April 2018, were systematically reviewed. Three electronic databases, PubMed, EMBASE, and the Cochrane Central Register, were searched. RESULTS Out of the 2844 studies identified, 305 had a full text evaluation and 27 studies met the criteria to be included in this analysis. All but one were retrospective studies. The 10-yr local control (LC) rate ranged from 71% to 100%. The 10-yr progression-free-survival rate ranged from 55% to 97%. The prescription dose ranged typically between 12 and 15 Gy, delivered in a single fraction. Toxicity rate was generally low. CONCLUSION The current literature supporting SRS for benign intracranial meningioma lacks level I and II evidence. However, when summarizing the large number of level III studies, it is clear that SRS can be recommended as an effective evidence-based treatment option (recommendation level II) for grade 1 meningioma.

• Publisher: Ovid Technologies (Wolters Kluwer Health),Oxford University Press,Copyright by the Congress of Neurological Surgeons,Wolters Kluwer Health, Inc
• Subject: Analysis / Associations, institutions, etc / Brain Cancer / Brain Disorders / Cancer / Clinical practice guidelines / Clinical Sciences / Drug dosages / Editor's Choice / Evidence-based medicine / Female / Female; Humans; Male; Meningeal Neoplasms/radiotherapy; Meningioma/radiotherapy; Radiosurgery/methods; Treatment Outcome; Fractionated radiosurgery; Guidelines; Hypofractionated stereotactic radiotherapy; Meningioma; Multisession-radiosurgery; Radiosurgery; Systematic review / Fractionated radiosurgery / Guidelines / Humans / Hypofractionated stereotactic radiotherapy / Male / Medical prognosis / Meningeal Neoplasms / Meningeal Neoplasms - radiotherapy / Meningioma / Meningioma - radiotherapy / Meta-analysis / Multisession-radiosurgery / Neurology & Neurosurgery / Neurosciences / Neurosurgery / Oncology / Patients / Practice guidelines (Medicine) / Radiation therapy / Radiosurgery / Radiosurgery - methods / Rare Diseases / Review / Sinuses / Societies / Surgery / Systematic review / Treatment Outcome / Tumors