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Near-infrared reflectance bull's eye maculopathy as an early indication of hydroxychloroquine toxicity
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Near-infrared reflectance bull's eye maculopathy as an early indication of hydroxychloroquine toxicity
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Journal Article
Near-infrared reflectance bull's eye maculopathy as an early indication of hydroxychloroquine toxicity
2015
Overview
In some patients, hydroxychloroquine ocular toxicity may progress even following cessation of therapy. Any leverage the clinician may use to allow earlier detection may avert significant vision loss.
We report three cases suggesting that bull's eye maculopathy seen on near-infrared reflectance with a confocal scanning laser ophthalmoscope could be an early, objective manifestation of hydroxychloroquine ocular toxicity, and with progression of the disease this near-infrared \"bull's eye\" change may disappear.
Alerting clinicians to this observation may allow a larger case series to corroborate the hypothesis that bull's eye maculopathy detected by near-infrared reflectance may represent an early sign of hydroxychloroquine toxicity.
