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Morcellation and risk of malignancy in presumed ovarian fibromas/fibrothecomas
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Morcellation and risk of malignancy in presumed ovarian fibromas/fibrothecomas
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Morcellation and risk of malignancy in presumed ovarian fibromas/fibrothecomas
Morcellation and risk of malignancy in presumed ovarian fibromas/fibrothecomas
Journal Article

Morcellation and risk of malignancy in presumed ovarian fibromas/fibrothecomas

2016
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Overview
Even if the benign nature of a mass is stated with a high level of diagnostic confidence or if several reassuring ultrasound features are present, the risk of malignancy exceeds the 0·3% risk of morcellating an unsuspected uterine sarcoma reported by the FDA. Characteristic present Characteristic absent Postmenopausal 9/123 (7%) 4/58 (7%) Increased CA125 (>=35 U/mL) 5/33 (15%) 4/86 (5%) Largest diameter of lesion (>=55 mm)* 8/92 (9%) 5/89 (6%) Lesion volume (>=58·4 mL)* 7/91 (8%) 6/90 (7%) Pain during examination[dagger] 2/29 (7%) 11/152 (7%) Bilateral lesions 2/16 (13%) 11/165(7%) Irregular walls 1/8 (13%) 12/173 (7%) Acoustic shadows 4/105 (4%) 9/76 (12%) Ascites 2/11 (18%) 11/170 (7%) Free fluid in the Pouch of Douglas 5/69 (7%) 8/112 (7%) Colour score 3-4 (moderate to abundant vascularisation) 3/49 (6%) 10/132 (8%) Typical appearance (colour score 1 or 2 plus acoustic shadows plus regular walls) 2/78 (3%) 11/103 (11%) Table 1 Number of malignant cases depending on the presence or absence of certain ultrasound features and clinical characteristics in solid tumours judged to be fibro(theco)mas