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Towards an HIV cure: a global scientific strategy

by Poli, Guido , Deeks, Steven G , Martinez-Picado, Javier , Stevenson, Mario , Cairns, Scott , Mellors, John , Van Lint, Carine , Berkhout, Ben , Katlama, Christine , Lederman, Michael , Markowitz, Martin , Lafeuillade, Alain , Woolfrey, Ann , Autran, Brigitte , Verdin, Eric , Barré-Sinoussi, Françoise , Benkirane, Monsef , Di Mascio, Michele , Peterlin, Matija , Chun, Tae-Wook , Maldarelli, Frank , Margolis, David , Landay, Alan , Telenti, Amalio , Chomont, Nicolas , Lewin, Sharon R , Palmer, Sarah , Rouzioux, Christine , Zaia, John , Silvestri, Guido , Routy, Jean-Pierre , Moreno, Santiago , O'Doherty, Una , Mullins, James I , Penicaud, Marie-Capucine , Churchill, Melissa

in 631/250/249/1570/1901 / 631/326/596/2564 / 692/308/575 / 692/700/565/1436 / Acquired immune deficiency syndrome / AIDS / AIDS (Disease) / AIDS research / Antiretroviral agents / Antiretroviral drugs / antiretroviral therapy / Antiretroviral Therapy, Highly Active - methods / Biomedical and Life Sciences / Biomedicine / Care and treatment / Drug therapy / HIV / HIV - physiology / HIV infection / HIV Infections - drug therapy / HIV Infections - virology / Hospitals / Human immunodeficiency virus / Humans / Immunology / Infection / Infections / Medical research / Memory / opinion-2 / Planning / Public health / Translation / Virus Latency - drug effects / Virus Replication - drug effects / Working groups / World health

2012

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2012

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2012

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Journal Article

Towards an HIV cure: a global scientific strategy

Poli, Guido,

Deeks, Steven G,

Martinez-Picado, Javier,

Stevenson, Mario,

Cairns, Scott,

Mellors, John,

Van Lint, Carine,

Berkhout, Ben,

Katlama, Christine,

Lederman, Michael,

Markowitz, Martin,

Lafeuillade, Alain,

Woolfrey, Ann,

Autran, Brigitte,

Verdin, Eric,

Barré-Sinoussi, Françoise,

Benkirane, Monsef,

Di Mascio, Michele,

Peterlin, Matija,

Chun, Tae-Wook,

Maldarelli, Frank,

Margolis, David,

Landay, Alan,

Telenti, Amalio,

Chomont, Nicolas,

Lewin, Sharon R,

Palmer, Sarah,

Rouzioux, Christine,

Zaia, John,

Silvestri, Guido,

Routy, Jean-Pierre,

Moreno, Santiago,

O'Doherty, Una,

Mullins, James I,

Penicaud, Marie-Capucine,

Churchill, Melissa

2012

Overview

The development of effective antiretroviral therapies has greatly improved the disease prognosis for patients with HIV. However, the limitations of these therapies have renewed interest in developing alternative treatment strategies. Here, a group of experts from the International AIDS Society discuss the research steps that need to be taken to achieve the ultimate objective — a cure for HIV. Given the limitations of antiretroviral therapy and recent advances in our understanding of HIV persistence during effective treatment, there is a growing recognition that a cure for HIV infection is both needed and feasible. The International AIDS Society convened a group of international experts to develop a scientific strategy for research towards an HIV cure. Several priorities for basic, translational and clinical research were identified. This Opinion article summarizes the group's recommended key goals for the international community.

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Publisher

Nature Publishing Group UK,Nature Publishing Group

Subject

631/250/249/1570/1901

/ 631/326/596/2564

/ 692/308/575

/ 692/700/565/1436

/ Acquired immune deficiency syndrome

/ AIDS

/ AIDS (Disease)