Journal Article

Exploring Bioactive Compounds in Brown Seaweeds Using Subcritical Water: A Comprehensive Analysis

Ye-Ryeon Shin, Hideki Kishimura, Ji-Min Han, Hee-Jeong Lee, Vikash Roy, Byung-Soo Chun, Ye-Seul Park, Jin-Seok Park, Sin-Won Park, Yu-Na Shin, Yuya Kumagai

2023

Overview

In this study, we characterized the bioactive properties of three important brown seaweed species, Sargassum thunbergii, Undaria pinnatifida, and Saccharina japonica, by subcritical water extraction (SWE), as these species are well known for their beneficial health effects. Their physiochemical properties, including potential antioxidant, antihypertensive, and α-glucosidase inhibitory activity, and the antibacterial activity of the hydroysates were also analyzed. The highest total phlorotannin, total sugar content, and reducing sugar content in the S. thunbergii hydrolysates were 38.82 ± 0.17 mg PGE/g, 116.66 ± 0.19 mg glucose/g dry sample, and 53.27 ± 1.57 mg glucose/g dry sample, respectively. The highest ABTS+ and DPPH antioxidant activities were obtained in the S. japonica hydrolysates (124.77 ± 2.47 and 46.35 ± 0.01 mg Trolox equivalent/g, respectively) and the highest FRAP activity was obtained in the S. thunbergii hydrolysates (34.47 ± 0.49 mg Trolox equivalent/g seaweed). In addition, the seaweed extracts showed antihypertensive (≤59.77 ± 0.14%) and α-glucosidase inhibitory activity (≤68.05 ± 1.15%), as well as activity against foodborne pathogens. The present findings provide evidence of the biological activity of brown seaweed extracts for potential application in the food, pharmaceutical, and cosmetic sectors.

• Publisher: MDPI AG,MDPI
• Subject: Algae / alpha-Glucosidases / Antibacterial activity / antibacterial properties / Antibiotics / Antihypertensive Agents / Antihypertensives / Antimicrobial agents / Antioxidants / Bioactive compounds / Biological activity / Biology (General) / brown seaweed / brown seaweed; subcritical water extraction; bioactive compounds; biological activity / Cancer / Carbohydrates / Chemical properties / Cosmetics / Efficiency / Equivalence / Extraction (Chemistry) / Glucose / Glucosidase / Health aspects / Hot water / Hydrolysates / Identification and classification / macroalgae / Marine algae / Metabolites / Methods / Organic compounds / Oxidation / Pathogens / phlorotannins / Physiochemistry / Plant Extracts / QH301-705.5 / Saccharides / Saccharina japonica / Sargassum thunbergii / Seaweed / Seaweeds / Solvents / subcritical water extraction / Sugar / sugar content / Temperature / Undaria pinnatifida / Vitamin E / Water / α-Glucosidase